National Live Cell Scanning Platform for Nanoparticle Tracking

国家纳米粒子追踪活细胞扫描平台

• 批准号: LE150100177
• 负责人: Dr Yiqing Lu
• 金额: $ 29.34万
• 依托单位: Macquarie University
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Infrastructure, Equipment and Facilities
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LE150100177
• 关键词: National; Live; Cell; Scanning; Platform

National live cell scanning platform for nanoparticle tracking: The aim of the project is to establish a multi-disciplinary, multi-user, self-correlated scanning facility to reach a new level of temporal and spatial precision for real-time tracking and quantification of biomolecules and nanoparticles within large populations of living cells. The facility will consist of a live-cell spinning-disc confocal microscope, a correlated biological atomic force microscope, and remote access facilities. It is expected that with superior optical characterisation and mechanical manipulation, the automated orthogonal scanning facility will open new avenues to reveal unprecedented information from biological and pathological processes. The collaborative facility will support world-class researchers in the multi-disciplinary areas of physical, material and life sciences, placing Australia at the forefront of nanoscale biophotonics.

国家活细胞扫描纳米颗粒跟踪平台：该项目的目标是建立一个多学科、多用户、自相关的扫描设施，以达到新的时间和空间精度水平，用于实时跟踪和量化大量活细胞中的生物分子和纳米颗粒。该设施将包括一个活细胞旋转盘共聚焦显微镜，一个相关的生物原子力显微镜，以及远程访问设施。预计凭借卓越的光学特性和机械操作，自动正交扫描设备将开辟新的途径，揭示来自生物和病理过程的前所未有的信息。该合作设施将支持物理、材料和生命科学等多学科领域的世界级研究人员，使澳大利亚处于纳米级生物光子学的前沿。