Investigating GPCR:RAMP interactions using nanobodies

使用纳米抗体研究 GPCR:RAMP 相互作用

• 批准号: BB/R016755/1
• 负责人: David Poyner
• 金额: $ 3.57万
• 依托单位: Aston University
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2018
• 资助国家: 英国
• 起止时间: 2018 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=BB%2FR016755%2F1
• 关键词: Investigating; GPCR; RAMP; interactions; using

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

目前GtR中并没有提供所有资助研究的摘要。这通常是因为在提交提案时不需要摘要，但也可能是因为它包含敏感信息，如个人详细信息。

项目成果

Ligand-induced conformational changes in a SMALP-encapsulated GPCR

• DOI: 10.1016/j.bbamem.2020.183235
• 发表时间: 2020-06-01
• 期刊: BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
• 影响因子: 3.4
• 作者: Routledge, Sarah J.;Jamshad, Mohammed;Wheatley, Mark
• 通讯作者: Wheatley, Mark

Differences in SMA-like polymer architecture dictate the conformational changes exhibited by the membrane protein rhodopsin encapsulated in lipid nano-particles.

• DOI: 10.1039/d1nr02419a
• 发表时间: 2021-08-21
• 期刊: Nanoscale
• 影响因子: 6.7
• 作者: Grime RL ;Logan RT ;Nestorow SA ;Sridhar P ;Edwards PC ;Tate CG ;Klumperman B ;Dafforn TR ;Poyner DR ;Reeves PJ ;Wheatley M
• 通讯作者: Wheatley M