THE ROLE OF RAMPS IN LIGAND-ENGENDERED SIGNAL BIAS OF SECRETIN-LIKE RECEPTORS

斜坡在促胰液素样受体配体产生的信号偏差中的作用

• 批准号: BB/M000176/1
• 负责人: David Poyner
• 金额: $ 3.94万
• 依托单位: Aston University
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2015
• 资助国家: 英国
• 起止时间: 2015 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=BB%2FM000176%2F1
• 关键词: ROLE; RAMPS; LIGAND; ENGENDERED; SIGNAL

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

目前GtR中并没有所有资助研究的摘要。这通常是因为在提交提案时不需要摘要，但也可能是因为摘要中包含个人详细信息等敏感信息。

项目成果

Receptor Activity-modifying Proteins 2 and 3 Generate Adrenomedullin Receptor Subtypes with Distinct Molecular Properties.

• DOI: 10.1074/jbc.m115.688218
• 发表时间: 2016-05-27
• 期刊: The Journal of biological chemistry
• 作者: Watkins HA;Chakravarthy M;Abhayawardana RS;Gingell JJ;Garelja M;Pardamwar M;McElhinney JM;Lathbridge A;Constantine A;Harris PW;Yuen TY;Brimble MA;Barwell J;Poyner DR;Woolley MJ;Conner AC;Pioszak AA;Reynolds CA;Hay DL
• 通讯作者: Hay DL

The Role of ICL1 and H8 in Class B1 GPCRs; Implications for Receptor Activation.

ICL1 和 H8 在 B1 类 GPCR 中的作用；

• DOI: 10.17863/cam.80814
• 发表时间: 2021
• 作者: Winfield I

The effects of RAMPs upon cell signalling

• DOI: 10.1016/j.mce.2017.03.033
• 发表时间: 2017-07
• 期刊: Molecular and Cellular Endocrinology
• 影响因子: 4.1
• 作者: S. Routledge;G. Ladds;D. Poyner

Receptor Activity-modifying Protein-directed G Protein Signaling Specificity for the Calcitonin Gene-related Peptide Family of Receptors.

• DOI: 10.1074/jbc.m116.751362
• 发表时间: 2016-10-14
• 期刊: The Journal of biological chemistry
• 作者: Weston C;Winfield I;Harris M;Hodgson R;Shah A;Dowell SJ;Mobarec JC;Woodlock DA;Reynolds CA;Poyner DR;Watkins HA;Ladds G
• 通讯作者: Ladds G

Modulation of Glucagon Receptor Pharmacology by Receptor Activity-modifying Protein-2 (RAMP2).

• DOI: 10.1074/jbc.m114.624601
• 发表时间: 2015-09-18
• 期刊: The Journal of biological chemistry
• 作者: Weston C;Lu J;Li N;Barkan K;Richards GO;Roberts DJ;Skerry TM;Poyner D;Pardamwar M;Reynolds CA;Dowell SJ;Willars GB;Ladds G
• 通讯作者: Ladds G