New potato varieties with late blight resistance, reduced bruising and improved processing quality

具有抗晚疫病、减少擦伤并提高加工质量的马铃薯新品种

• 批准号: BB/S018832/1
• 负责人: Jonathan Jones
• 金额: $ 42.09万
• 依托单位: University of East Anglia
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2019
• 资助国家: 英国
• 起止时间: 2019 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=BB%2FS018832%2F1
• 关键词: New; potato; varieties; late; blight

Late blight (LB) is the most important potato disease. Tuber bruising also causes losses and cold-induced sweetening (CIS) in tubers can result in acrylamide formation after high-temperature cooking to make crisps or chips. We are making genetically modified Maris Piper (MP) potato lines carrying 3 LB resistance genes (so the resistance should be more durable) and a "silencing" construct to prevent bruising and CIS in tubers. From screening >100 such MP lines, in 2 years of field trials, we will identify a lead line ("PiperPlus") that carries all LB resistance genes, and with bruise and CIS-prevention in tubers. We will select 20-30 lines that carry the desired traits and suitable molecular characteristics. These will be tested in the field in 2019, to prioritize 5-10 lines for larger scale field trials in 2020. We will thoroughly assess LB resistance, tuber properties, yield and molecular properties to select a lead line suitable for regulatory appraisal and commercialisation.

晚疫病是马铃薯最重要的病害。块茎损伤也会导致损失，块茎中的冷诱导甜味（CIS）可能导致在高温烹饪后形成丙烯酰胺，以制作薯片或薯片。我们正在制作转基因Maris Piper（MP）马铃薯品系，该品系携带3个LB抗性基因（因此抗性应该更持久）和一个“沉默”结构，以防止块茎中的瘀伤和CIS。通过在2年的田间试验中筛选>100个这样的MP系，我们将鉴定出携带所有LB抗性基因并且在块茎中具有擦伤和CIS预防的先导系（“BMPPlus”）。我们将选择20-30个具有所需性状和合适分子特征的品系。这些将在2019年进行实地测试，并在2020年优先考虑5-10条线路进行更大规模的实地试验。我们将全面评估LB抗性、块茎特性、产量和分子特性，以选择适合监管评估和商业化的先导系。

项目成果

Solanum americanum genome-assisted discovery of immune receptors that detect potato late blight pathogen effectors.

• DOI: 10.1038/s41588-023-01486-9
• 发表时间: 2023-09
• 期刊: NATURE GENETICS
• 影响因子: 30.8
• 作者: Lin, Xiao;Jia, Yuxin;Heal, Robert;Prokchorchik, Maxim;Sindalovskaya, Maria;Olave-Achury, Andrea;Makechemu, Moffat;Fairhead, Sebastian;Noureen, Azka;Heo, Jung;Witek, Kamil;Smoker, Matthew;Taylor, Jodie;Shrestha, Ram-Krishna;Lee, Yoonyoung;Zhang, Chunzhi;Park, Soon Ju;Sohn, Kee Hoon;Huang, Sanwen;Jones, Jonathan D. G.
• 通讯作者: Jones, Jonathan D. G.