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MOLECULAR APPROACHES TO CELL ULTRASTRUCTURE

MOLECULAR APPROACHES TO CELL ULTRASTRUCTURE
细胞超微结构的分子方法
批准号:
3268878
负责人:
S J SINGER
金额:
$25.34万
依托单位国家:
美国
项目类别:
财政年份:
1978
资助国家:
美国
项目状态:
已结题
起止时间:
1978-05-01 至 1995-04-30

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中文摘要
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英文摘要
The long-term objectives of this research program are to explore the molecular bases of a number of different cellular phenomena, all of which have in common the involvement of cell membranes. The specific problems to be investigated, which are outgrowths of our past studies on this grant, include the following: 1) the mechanisms of intracellular transport of secretory and integral membrane proteins from the endoplasmic reticulum to the Golgi apparatus; 2) the role of newly discovered membrane-bound tyrosin kinases, which are prominent components in the chick embryo, in embryonic development; 3)the mechanisms of signal transduction across membranes that result in massive cytoplasmic rearrangements and polarization inside the affected cells.
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BASIC BIOCHEMICAL AND BIOLOGICAL MECHANISMS IN CANCER
BASIC BIOCHEMICAL AND BIOLOGICAL MECHANISMS IN CANCER
BASIC BIOCHEMICAL AND BIOLOGICAL MECHANISMS IN CANCER
TRANSMISSION ELECTRON MICROSCOPE
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