MOLECULAR APPROACHES TO CELL ULTRASTRUCTURE
MOLECULAR APPROACHES TO CELL ULTRASTRUCTURE
批准号:
3268870
负责人:
S J SINGER
金额:
$28.09万
依托单位国家:
美国
项目类别:
财政年份:
1978
资助国家:
美国
项目状态:
已结题
起止时间:
1978-05-01 至 1991-04-30
关键词:
autoradiography brush border membrane cell cell interaction cell membrane cell type chemical models cytoskeleton electron microscopy fibroblasts fluorescent dye /probe histochemistry /cytochemistry hybridomas immunochemistry immunoelectron microscopy immunofluorescence technique lymphocyte membrane activity membrane permeability membrane reconstitution /synthesis membrane structure molecular rearrangement monoclonal antibody muscle proteins neoplastic transformation pinocytosis radiotracer stainings surface antigens temperature sensitive mutant tissue /cell culture
中文摘要
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英文摘要
We will carry out several projects: 1) the high resolution immunoelectron
microscopic localization of a number of recently discovered junctional
proteins at a variety of membrane - microfilament attachment sites; 2)
continued search for integral membrane proteins at these sites, using a
monoclonal antibody approach combined with selection by immunocytochemical
localization; 3) continued studies of the immunolocalization of
phosphotyrosine residues of proteins inside intact cells, using specific
monoclonal antibodies generated to phosphotyrosine; 4) the extension of our
immunoelectron microscopic studies of the intracellular pathways of serum
protein secretion in cultured hepatocytes; and 5) the exploration of the
molecular basis for the association which we have demonstrated between the
Golgi apparatus and the microtubule organizing center in cells.
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BASIC BIOCHEMICAL AND BIOLOGICAL MECHANISMS IN CANCER
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批准号:3533052
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项目类别:
-
资助金额:$13.49万
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财政年份:1990
-
负责人:S J SINGER
-
依托单位:
BASIC BIOCHEMICAL AND BIOLOGICAL MECHANISMS IN CANCER
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批准号:3533053
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项目类别:
-
资助金额:$12.19万
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财政年份:1990
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负责人:S J SINGER
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依托单位:
BASIC BIOCHEMICAL AND BIOLOGICAL MECHANISMS IN CANCER
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批准号:3533047
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项目类别:
-
资助金额:$16.17万
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财政年份:1990
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负责人:S J SINGER
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依托单位:
TRANSMISSION ELECTRON MICROSCOPE
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批准号:3520386
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项目类别:
-
资助金额:$21.8万
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财政年份:1989
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负责人:S J SINGER
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依托单位:
BASIC BIOCHEMICAL AND BIOLOGICAL MECHANISMS IN CANCER
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批准号:3533051
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项目类别:
-
资助金额:$12.63万
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财政年份:1984
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负责人:S J SINGER
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依托单位:
BASIC BIOCHEMICAL AND BIOLOGICAL MECHANISMS IN CANCER
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批准号:3533048
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项目类别:
-
资助金额:$10.01万
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财政年份:1984
-
负责人:S J SINGER
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依托单位:
BASIC BIOCHEMICAL AND BIOLOGICAL MECHANISMS IN CANCER
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批准号:3533050
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项目类别:
-
资助金额:$12.96万
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财政年份:1984
-
负责人:S J SINGER
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依托单位:
BASIC BIOCHEMICAL AND BIOLOGICAL MECHANISMS IN CANCER
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批准号:3533049
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项目类别:
-
资助金额:$11.24万
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财政年份:1984
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负责人:S J SINGER
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依托单位:
MOLECULAR APPROACHES TO CELL ULTRASTRUCTURE
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批准号:3268871
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项目类别:
-
资助金额:$23.08万
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财政年份:1978
-
负责人:S J SINGER
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依托单位:
MOLECULAR APPROACHES TO CELL ULTRASTRUCTURE
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批准号:2170469
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项目类别:
-
资助金额:$26.34万
-
财政年份:1978
-
负责人:S J SINGER
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依托单位:
MOLECULAR APPROACHES TO CELL ULTRASTRUCTURE
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批准号:3268874
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项目类别:
-
资助金额:$32.49万
-
财政年份:1978
-
负责人:S J SINGER
-
依托单位:
MOLECULAR APPROACHES TO CELL ULTRASTRUCTURE
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批准号:3268875
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项目类别:
-
资助金额:$33.47万
-
财政年份:1978
-
负责人:S J SINGER
-
依托单位:
MOLECULAR APPROACHES TO CELL ULTRASTRUCTURE
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批准号:3268877
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项目类别:
-
资助金额:$24.14万
-
财政年份:1978
-
负责人:S J SINGER
-
依托单位:
MOLECULAR APPROACHES TO CELL ULTRASTRUCTURE
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批准号:3268878
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项目类别:
-
资助金额:$25.34万
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财政年份:1978
-
负责人:S J SINGER
-
依托单位:
MOLECULAR APPROACHES TO CELL ULTRASTRUCTURE
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批准号:3268873
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项目类别:
-
资助金额:$30.11万
-
财政年份:1978
-
负责人:S J SINGER
-
依托单位:
MOLECULAR APPROACHES TO CELL ULTRASTRUCTURE
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批准号:3268876
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项目类别:
-
资助金额:$35.38万
-
财政年份:1978
-
负责人:S J SINGER
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依托单位:
MOLECULAR APPROACHES TO CELL ULTRASTRUCTURE
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批准号:3268872
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项目类别:
-
资助金额:$24.59万
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财政年份:1978
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负责人:S J SINGER
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依托单位:
STRUCTURE OF ANTIBODY MOLECULES AND CELL MEMBRANES
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批准号:3124298
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项目类别:
-
资助金额:$17.2万
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财政年份:1975
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负责人:S J SINGER
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依托单位:
STRUCTURE OF ANTIBODY MOLECULES AND CELL MEMBRANES
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批准号:3124297
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项目类别:
-
资助金额:$16.61万
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财政年份:1975
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负责人:S J SINGER
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依托单位:
STRUCTURE OF ANTIBODY MOLECULES AND CELL MEMBRANES
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批准号:3124300
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项目类别:
-
资助金额:$20.46万
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财政年份:1975
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负责人:S J SINGER
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依托单位:
海外基金