GENETIC CONSEQUENCES OF POPULATION STRUCTURE

拟议研究的总体目标是了解 一个物种进化过程中的种群结构 人口结构 是繁殖个体在内部和内部的分布方式 德谟及其在德谟之间的运动模式。 人群细分 对生态和遗传都有影响。 的遗传效应 随机遗传漂变可导致阵列的遗传分化 当地的部落。 遗传分化的速度和程度取决于 当地繁殖的成虫数量以及 分散在当地人之间。 细分生态效应 影响族群内部和族群之间的选择过程。 生态 和遗传效应相互作用，以确定内部的相对重要性， 和种群间选择对物种的整体进化的影响。 我们 结合实验研究，使用实验室人口的面粉， 甲虫（拟谷盗属），与相关遗传的理论模型 现象来研究那些 可能会对一个物种的进化产生重要影响。 进化是结构化的人口是赖特的中心特征 进化的平衡理论，最全面的 遗传学和进化论。 这项研究将提供一个 赖特理论的实验基础，特别强调 基因相互作用在适应性进化的“中间阶段”中的作用。

The overall objective of the proposed research is to understand the role of population structure in the evolution of a species. Population structure is the way in which breeding individuals are distributed within and among demes and their pattern of movement among demes. Population subdivision has both ecological and genetic consequences. The genetic effects of random genetic drift can result in the genetic differentiation of an array of local demes. The rate and degree of genetic differentiation depend on the numbers of locally breeding adults and the amount and pattern of dispersion among locals demes. the ecological effects of subdivision influence the process of selection within and among demes. The ecological and genetic effects interact to determine the relative importance of intra and interdemic selection to the overall evolution of the species. We are combining experimental studies, using laboratory populations of flour beetles (genus Tribolium), with theoretical models of the relevant genetic phenomena to investigate those kinds of population structures that are likely to have important evolutionary consequences for a species. Evolution is structured population is the central feature of Wright's Shifting Balance Theory of Evolution, one of the most comprehensive theories of genetics and evolution. The proposed research will provide an experimental foundation for Wright's theory with special emphasis on the role of gene interactions in the "interdemic-phase" of adaptive evolution.