Bringing Laser Capture Microscopy Technology to the University of Bristol

将激光捕获显微镜技术引入布里斯托大学

• 批准号: BB/W020114/1
• 负责人: Oscar Cordero Llana
• 金额: $ 31.07万
• 依托单位: University of Bristol
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2022
• 资助国家: 英国
• 起止时间: 2022 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=BB%2FW020114%2F1
• 关键词: Bringing; Laser; Capture; Microscopy; Technology

We are a multidisciplinary team of researchers working on a wide range of topics. We study the heart, kidney function, brain wiring and regeneration, wound healing, stress, etc. For our work we need to go from single cells to whole animals and human participants. This means we need to study complex biological samples that contain multiple types of cells in complex environments. In this proposal we are requesting an advanced Laser Capture-Micromanipulation platform that will allow us to zoom in at individual cells. We want not just to isolate these cells but also to manipulate them using microscopic laser tweezers and to do this under carefully controlled experimental conditions. This would represent a fantastic opportunity to expand our research so that we can continue to produce transformative research with real potential to improve health and wellbeing across the life course.

我们是一个多学科的研究团队，致力于广泛的主题。我们研究心脏，肾脏功能，大脑布线和再生，伤口愈合，压力等，对于我们的工作，我们需要从单个细胞到整个动物和人类参与者。这意味着我们需要在复杂的环境中研究包含多种类型细胞的复杂生物样本。在这个提案中，我们要求一个先进的激光捕获显微操作平台，使我们能够放大单个细胞。我们不仅想分离这些细胞，还想用显微激光镊子操纵它们，并在严格控制的实验条件下进行。这将是一个扩大我们研究的绝佳机会，这样我们就可以继续进行具有真实的潜力的变革性研究，以改善整个生命过程中的健康和福祉。