Engineering an artificial protein molecular motor

设计人造蛋白质分子马达

• 批准号: DP170103153
• 负责人: Prof Paul Curmi
• 金额: $ 26.66万
• 依托单位: The University of New South Wales
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 2020-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP170103153
• 关键词: Engineering; artificial; protein; molecular; motor

This project aims to use non-motor protein building blocks to construct an artificial protein motor. Nature already uses nanotechnology as the basis for all its machinery, and uses proteins to construct machines. Each protein component in the motor will have a well-understood function; this artificial protein will elucidate how it converts chemical energy to motion. This process is not understood as molecular motors do not obey the same principles as macroscopic machines. Comparing the artificial motor with biological motors will provide insight into the workings of natural motors. This project should lead to molecular motors for nanobiotechnology.

该项目旨在使用非马达蛋白质构建块来构建人造蛋白质马达。大自然已经使用纳米技术作为其所有机器的基础，并使用蛋白质来构建机器。马达中的每个蛋白质成分都有众所周知的功能；这种人造蛋白质将阐明它是如何将化学能转化为运动的。这一过程没有被理解，因为分子马达不遵守与宏观机器相同的原理。将人造马达与生物马达进行比较，将有助于我们深入了解天然马达的工作原理。这个项目应该会导致纳米生物技术的分子马达。