X-ray facility for protein crystallography
X-ray facility for protein crystallography
批准号:
LE190100165
负责人:
Prof Paul Curmi
金额:
$27.18万
依托单位国家:
澳大利亚
项目类别:
Linkage Infrastructure, Equipment and Facilities
财政年份:
2019
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2019-01-01 至 2019-12-31
中文摘要
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英文摘要
This project aims to establish an X-ray crystallography facility to enhance the productivity of structural biology.. The facility will increase the speed and success rate for protein structure determination. It is expected to produce protein crystals, optimise them for X-ray diffraction quality and determine initial structures prior to ultimate analysis at the Australian Synchrotron for maximal resolution. The goal of this facility is to accelerate the rate of macromolecular structure determination, which will provide the basis for the future development of biotechnology and biopharmaceuticals. The resulting protein structures will enhance research in molecular and cell biology, synthetic biology and chemistry, biochemistry and the design of inhibitors for biotechnology and biopharmaceuticals.
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会议论文
Flick the biological quantum switch: light controls photosynthetic proteins
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批准号:DP180103964
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项目类别:Discovery Projects
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资助金额:$28.54万
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财政年份:2018
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负责人:Prof Paul Curmi
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依托单位:
Engineering an artificial protein molecular motor
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批准号:DP170103153
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项目类别:Discovery Projects
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资助金额:$26.66万
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财政年份:2017
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负责人:Prof Paul Curmi
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依托单位:
Protein structure controls light harvesting in photosynthetic light algae
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批准号:DP150102580
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项目类别:Discovery Projects
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资助金额:$25.86万
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财政年份:2015
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负责人:Prof Paul Curmi
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依托单位:
Structural studies on chaperone protein machines from an Antarctic archeon
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批准号:DP120102285
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项目类别:Discovery Projects
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资助金额:$21.48万
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财政年份:2012
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负责人:Prof Paul Curmi
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依托单位:
Evolution of the light harvesting system in cryptophyte algae: protein structure to quantum coherence
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批准号:DP110104725
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项目类别:Discovery Projects
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资助金额:$23.22万
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财政年份:2011
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负责人:Prof Paul Curmi
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依托单位:
Structural and pharmaceutical studies on a novel human protein, MIC-1
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批准号:LP0883838
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项目类别:Linkage Projects
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资助金额:$36.04万
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财政年份:2009
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负责人:Prof Paul Curmi
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依托单位:
Ultrahigh resolution crystallography and ultrafast laser spectroscopy to uncover the evolution and mechanisms of a unique algal light harvesting system
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批准号:DP0881251
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项目类别:Discovery Projects
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资助金额:$19.73万
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财政年份:2008
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负责人:Prof Paul Curmi
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依托单位:
X-ray crystallography resource for membrane proteins and large macromolecular complexes
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批准号:LE0882295
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项目类别:Linkage Infrastructure, Equipment and Facilities
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资助金额:$15.0万
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财政年份:2008
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负责人:Prof Paul Curmi
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依托单位:
Crystallographic studies of CLIC family proteins
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批准号:nhmrc : 350844
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项目类别:NHMRC Project Grants
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资助金额:$33.71万
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财政年份:2005
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负责人:Prof Paul Curmi
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依托单位:
Probing the control and action of CLIC1/NCC27, an unusual chloride ion channel, by x-ray crystallography
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批准号:nhmrc : 209540
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项目类别:NHMRC Project Grants
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资助金额:$18.09万
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财政年份:2002
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负责人:Prof Paul Curmi
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依托单位:
X-ray Crystal Structure of NCC27: a Novel Chloride Channel Protein from Human Macrophages
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批准号:nhmrc : 990847
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项目类别:NHMRC Project Grants
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资助金额:$15.41万
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财政年份:1999
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负责人:Prof Paul Curmi
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依托单位:
海外基金