X-ray crystallography resource for membrane proteins and large macromolecular complexes

膜蛋白和大分子复合物的 X 射线晶体学资源

• 批准号: LE0882295
• 负责人: Prof Paul Curmi
• 金额: $ 15万
• 依托单位: The University of New South Wales
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Infrastructure, Equipment and Facilities
• 财政年份: 2008
• 资助国家: 澳大利亚
• 起止时间: 2008-01-01 至 2009-06-29
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LE0882295
• 关键词: ray; crystallography; resource; membrane; proteins

Structural biology is the underpinning of biotechnology, biopharmaceuticals and rational therapeutic design. The most successful technique for determining the structures of proteins and large macromolecular complexes is x-ray crystallography. This proposal will set up a network of state of the art resources in the Sydney region to capitalise on expertise in these areas. The facilities will foster basic research and collaborations with industry, which will enhance Australia's profile and commercialisation of research. The facility will enhance the usage of the Australian synchrotron, producing flagship projects on the edge of technical possibilities.

结构生物学是生物技术、生物制药和合理治疗设计的基础。测定蛋白质和大分子复合物结构最成功的技术是x射线晶体学。该提案将在悉尼地区建立一个最先进的资源网络，以利用这些领域的专业知识。这些设施将促进基础研究和与工业界的合作，这将提高澳大利亚的形象和研究的商业化。该设施将加强澳大利亚同步加速器的使用，在技术可能性的边缘产生旗舰项目。