IRON DEFICIENCY ANEMIA AND INFANT BEHAVIOR

缺铁性贫血和婴儿行为

• 批准号: 3312492
• 负责人: BETSY LOZOFF
• 金额: $ 34.79万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 1980
• 资助国家: 美国
• 起止时间: 1980-09-01 至 1995-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3312492
• 关键词: Central America; Guatemala; behavior test; child behavior; clinical trials; cognition; developmental neurobiology; developmental nutrition; diet therapy; dietary iron; disease /disorder prevention /control; human subject; human therapy evaluation; infant human (0-1 year); microcytic /hypochromic anemia; neuropsychological tests; nutrition related tag; placebos; preschool child (1-5); psychomotor function; videotape /videodisc

DESCRIPTION: (Adapted From The Applicant's Abstract) The proposed study addresses the clinical question of the behavioral effects of iron deficiency anemia. Earlier studies have demonstrated that altered behavior and lower developmental test scores do not improve with iron therapy and that behavioral differences are still present at school entry. Building on the research team's previous work in Costa Rica and Guatemala, this study seeks to further characterize specific behavioral alterations among iron deficient infants. The study has four specific aims: (1) to characterize specific behavioral alterations in iron deficient anemic infants; (2) to determine if iron deficiency anemia has different behavioral effects in the first versus the second year of life; (3) to determine if environmental stimulation plus iron therapy corrects the behavior of infants with iron deficiency anemia; and (4) to determine of therapeutic interventions are more effective in the first or the second year of life.

描述：（改编自申请人摘要）拟议的研究 解决了铁对行为影响的临床问题 贫血症。 早期的研究表明，改变行为 较低的发育测试分数并不能通过铁治疗得到改善， 行为差异在入学时仍然存在。 基础上 该研究小组先前在哥斯达黎加和危地马拉工作， 旨在进一步描述铁之间的特定行为改变， 缺陷儿 本研究有四个具体目标：（1） 缺铁性贫血婴儿的特定行为改变;（2） 确定缺铁性贫血是否有不同的行为影响， 第一年与第二年的生活;（3）以确定是否环境 刺激加铁剂治疗纠正铁婴儿的行为 缺乏性贫血;（4）确定治疗干预措施， 在生命的第一年或第二年更有效。