AROUSAL AND ATTENTION IN HIGH-RISK NEONATES

这个项目调查了唤醒和注意的组织在 疑似脑侮辱的高危新生儿。自脑侮辱以来 更有可能损害皮质下和脑干区域 由于这些地区更有可能是 与新生儿的唤醒和注意过程有关，我们假设 出血发生的早产儿越早，出血越严重 出血，改变注意力的可能性就越小，因为 性唤醒的变化。早熟程度不应影响这种互动 没有相应的大脑侮辱。婴儿将在NICU附近接受检测 放电以建立他们沿时间频率的视觉偏好 尺寸(1、2、4、8赫兹)。偏好函数将通过以下方式获得 观察对每个成员的注视持续时间 同时呈现具有所有刺激组合的刺激 平衡。跨刺激的线性偏好函数，当一个 健康的新生儿被喂养和包裹，如果婴儿接受测试，则颠倒过来 在喂奶之前和未被包裹或在暴露于 刺激。婴儿将被分成8组，每组12人(总人数为96人) 取决于：(1)BW和EGA证明的早熟程度，以及 (2)B超及脑干检查证实的出血严重程度 听觉诱发反应。唤醒之间的正常互动 偏好函数斜率中的条件应减少 脑损伤，而且损伤发生得越早 发展。经济复苏的进程，通过减少 NICU住院期间的神经和生命体征异常，以及 婴儿的神经行为和运动功能特征将是 在出院时测量以获得关于程度的额外证据 脑损伤的严重程度，作为替代，但二级评估 侮辱的解决办法。将使用这些措施进行对比，以 分析他们是如何受到唤醒和关注的影响的。

This project investigates the organization of arousal and attention in high-risk neonates suspected of suffering brain insult. Since brain insult is more likely to compromise subcortical and brainstem areas the earlier in development it occurs, and since these regions are more likely to be involved in arousal and attention processes in neonates, we hypothesize the earlier the prematurity when hemorrhage occurs and the more severe the hemorrhage, the less likely will be the ability to change attention as arousal changes. Degree of prematurity should not affect this interaction without corresponding brain insult. Infants will be tested near NICU discharge to establish their visual preferences along a temporal frequency dimension (1, 2, 4, 8 Hz). Preference functions will be obtained by observing the duration of fixation to each member of a pair of simultaneously presented stimuli with all combinations of stimuli balanced. The linear preference function across stimuli, found when a healthy neonate is fed and swaddled, is reversed if the infant is tested before feeding and unswaddled or tested after exposure to prior stimulation. Infants will be divided into 8 groups of 12 (Total N = 96) depending on: (1) the degree of prematurity evidenced by BW and EGA, and (2) the severity of hemorrhage evidenced by ultrasonography and brainstem auditory evoked responses. The normal interaction between arousal conditions in the slopes of the preference functions should be reduced by brain insult, and the more so the earlier the injury occurs in development. The course of recovery as estimated by the reduction in abnormal neurological and vital signs over the course of NICU stay, and the characteristics of the infants neurobehavioral and motor functions will be measured at discharge to obtain additional evidence as to the degree of severity of brain insult and as an alternative, but secondary estimate of resolution of insult. Contrasts will be conducted using these measures to analyze how they are affected by arousal and attention.