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A High Performance Direct Electron Imager

A High Performance Direct Electron Imager
高性能直接电子成像仪
批准号:
EP/H02834X/1
负责人:
Angus Kirkland
金额:
$17.1万
依托单位:
依托单位国家:
英国
项目类别:
Research Grant
财政年份:
2010
资助国家:
英国
项目状态:
已结题
起止时间:
2010 至 --

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中文摘要
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英文摘要
The development of Transmission Electron Microscopes (TEM's) has made tremendous progress in the last few years and these instruments are now routinely used in laboratories across the world to obtain structural data from many materials at resolutions beyond 100pm. However the detectors that are essential for digital recording of images, diffraction patterns and spectra are still based on old technology which limits the performance of these instruments (the detector gap ). The basic problem lies in the construction and operation of detectors which are based on Charge Coupled Devices (CCD's) similar to those used for optical imaging. CCD's are damaged if directly exposed to the electron beam and must be coupled to a scintillator which converts the beam electrons into photons. These photons are then recorded by the CCD. Previous research under an EPSRC funded project has developed an entirely new type of sensor that can be directly exposed to medium energy electrons as an alternative to indirect detection. This sensor has been shown to have a far greater sensitivity than indirectly coupled CCDs (it is capable of detecting single electrons) and has far higher resolution. In addition it can be operated in a counting mode providing an infinite dynamic range. These significantly improved characteristics will enhance the output from TEM's by providing less noisy digital images and spectra enabling materials to be studied with less radiation exposure. This is vitally important when the TEM is used to study many modern materials, such as semiconductors, catalysts and carbon based nanostructures which are often damaged in the electron beam. It will also be critical for imaging biological materials which are extremely electron sensitive and where the enhanced sensitivity will be of considerable benefit. We now intend to develop the commercial potential of this novel the 1D sensor through the construction of a functional 2D imaging as a commercial prototype. This will require fabrication of a large array 2D sensor using our existing technology, the integration of suitable readout electronics and the design and construction of a suitable mechanical / vacuum interface to form a prototype imaging system. We will then use this to demonstrate to investors the clear advantages of this technology over existing detectors in a range of application examples from both biology and materials science. All of these steps have been demonstrated to be technically feasible within the orginal project and are essential steps in realising the commercial potential of the sensor.
期刊论文(9)
专著(0)
科研奖励(0)
会议论文
Assessing the precision of strain measurements using electron backscatter diffraction--part 1: detector assessment.
使用电子背散射衍射评估应变测量的精度 - 第 1 部分:探测器评估。
DOI: 10.1016/j.ultramic.2013.08.005
发表时间: 2013
期刊: Ultramicroscopy
影响因子: 2.2
作者: [Britton TB]
通讯作者: Britton TB
Direct detection of electron backscatter diffraction patterns.
直接检测电子背散射衍射图案。
DOI: 10.1103/physrevlett.111.065506
发表时间: 2013
期刊: Physical review letters
影响因子: 8.6
作者: [Wilkinson AJ]
通讯作者: Wilkinson AJ
Imaging electron detectors for low-voltage TEM
用于低压 TEM 的成像电子探测器
DOI: 10.1088/1742-6596/241/1/012009
发表时间: 2010
期刊: Conference Series
影响因子: --
作者: [Moldovan G]
通讯作者: Moldovan G
1122 poster SILICON DIODE ARRAYS FOR SMALL FIELD QA AND STEREOTACTIC RADIOSURGERY/THERAPY VERIFICATION
1122海报用于小场质量保证和立体定向放射外科/治疗验证的硅二极管阵列
DOI: 10.1016/s0167-8140(11)71244-0
发表时间: 2011
期刊: Radiotherapy and Oncology
影响因子: 5.7
作者: [Manolopoulos S]
通讯作者: Manolopoulos S
6
    Rosalind Franklin Institute Correlated Imaging Phase 3
    • 批准号:
      EP/T033452/1
    • 项目类别:
      Research Grant
    • 资助金额:
      $366.33万
    • 财政年份:
      2020
    • 负责人:
      Angus Kirkland
    • 依托单位:
    Rosalind Franklin Institute Correlated Imaging Pump Priming
    • 批准号:
      EP/S001999/1
    • 项目类别:
      Research Grant
    • 资助金额:
      $998.43万
    • 财政年份:
      2018
    • 负责人:
      Angus Kirkland
    • 依托单位:
    Characterisation of Nanomaterials for Energy
    • 批准号:
      EP/K032518/1
    • 项目类别:
      Research Grant
    • 资助金额:
      $139.51万
    • 财政年份:
      2013
    • 负责人:
      Angus Kirkland
    • 依托单位:
    Platform Grant Support for Materials Characterisation at Oxford
    • 批准号:
      EP/F048009/1
    • 项目类别:
      Research Grant
    • 资助金额:
      $144.53万
    • 财政年份:
      2008
    • 负责人:
      Angus Kirkland
    • 依托单位:
    国内基金
    海外基金
    基于 Direct RNA sequencing 的 RNA 甲基化介导贻贝天然免疫调控的表观遗传机制研究
    • 批准号:
      LR22D060002
    • 项目类别:
      省市级项目
    • 资助金额:
      --
    • 批准年份:
      2021
    • 负责人:
      祁鹏志
    • 依托单位:
    新型滤波器综合技术-直接综合技术(Direct synthesis Technique)的研究及应用
    • 批准号:
      61671111
    • 项目类别:
      面上项目
    • 资助金额:
      58.0万元
    • 批准年份:
      2016
    • 负责人:
      肖飞
    • 依托单位: