Rapid Multiplexed Electronic Detection of Biomarkers for Point-of-Care Diagnostics (eTect)

用于即时诊断的生物标记物的快速多重电子检测 (eTect)

• 批准号: EP/I500928/1
• 负责人: Christoph Walti
• 金额: $ 12.91万
• 依托单位: University of Leeds
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2010
• 资助国家: 英国
• 起止时间: 2010 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=EP%2FI500928%2F1
• 关键词: Rapid; Multiplexed; Electronic; Detection; Biomarkers

The applicants have developed a novel technology based on low-cost semiconductor and molecular technologies that is able to detect minute protein traces, enabling rapid in-vitro detection of multiple biomarkers, including disease biomarkers, at low cost and without the need for complicated assays. This disruptive technology has the potential to impact upon a number of large, growing markets. Our technology offers easy-to-use, multiplexed electronic detection of biomarkers and has the potential to be used in hundreds, if not thousands, of diagnostic applications in multiple sectors including healthcare, veterinary, drug development, security and agrotech. More information is available on our website www.etect.co.uk.

申请人开发了一种基于低成本半导体和分子技术的新技术，能够检测微小的蛋白质痕迹，从而能够以低成本快速体外检测多种生物标志物，包括疾病生物标志物，而无需复杂的测定。这种颠覆性技术有可能影响许多不断增长的大型市场。我们的技术提供易于使用的生物标记物多重电子检测，并有潜力用于多个领域的数百甚至数千种诊断应用，包括医疗保健、兽医、药物开发、安全和农业技术。更多信息请访问我们的网站 www.etect.co.uk。

项目成果

Redox-induced conformational change in mercaptoalkanoic acid multilayer films.

氧化还原诱导的巯基链烷酸多层膜的构象变化。

• DOI: 10.1021/la300510x
• 发表时间: 2012
• 期刊: the ACS journal of surfaces and colloids
• 作者: Johnson S

Label-free electrochemical impedance biosensor to detect human interleukin-8 in serum with sub-pg/ml sensitivity.

• DOI: 10.1016/j.bios.2016.02.028
• 发表时间: 2016-06-15
• 期刊: Biosensors & bioelectronics
• 影响因子: 12.6
• 作者: Sharma R;Deacon SE;Nowak D;George SE;Szymonik MP;Tang AAS;Tomlinson DC;Davies AG;McPherson MJ;Wälti C
• 通讯作者: Wälti C

Improving the dielectric properties of ethylene-glycol alkanethiol self-assembled monolayers.

• DOI: 10.1021/la403983b
• 发表时间: 2014-02-11
• 期刊: Langmuir : the ACS journal of surfaces and colloids
• 作者: Zaccari I;Catchpole BG;Laurenson SX;Davies AG;Wälti C
• 通讯作者: Wälti C