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IN VITRO BIOCHEMICAL DIFFERENTIATION OF NERVE CELLS

IN VITRO BIOCHEMICAL DIFFERENTIATION OF NERVE CELLS
神经细胞的体外生化分化
批准号：
3394050
负责人：
NICHOLAS W SEEDS
金额：
$10.71万
依托单位：
UNIVERSITY OF COLORADO DENVER
依托单位国家：
美国
项目类别：
财政年份：
1976
资助国家：
美国
项目状态：
已结题
起止时间：
1976-09-01 至 1989-06-30
来源：
https://reporter.nih.gov/project-details/3394050
关键词：
autoradiography brain cell cell adhesion cell aggregation cell cell interaction cell differentiation cell migration cell sorting cerebellum chromatography electron microscopy electrophoresis electrophysiology embryo /fetus embryo /fetus tissue /cell culture gel electrophoresis histology hybridomas membrane activity monoclonal antibody myelination neuroanatomy neurochemistry neurons newborn animals plasminogen activator synapses tissue /cell culture

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中文摘要
翻译
调查的目的是阐明……的生化性质
英文摘要
Investigations will be directed at elucidating the biochemical nature of cell-cell interaction that influence development and differentiation in the central nervous system. Reaggregate and surface cultures of neonatal mouse cerebellum will be used to monitor biochemical and morphological development. The role of cell surface components in cell migration and myelination will be assessed using rabbit antisera or mouse hybridoma immunoglobulins directed against specific cell surface molecules. The role of plasminogen activator in granule cell migration will be examined both in vitro and in vivo using specific proteolytic inhibitors and antibodies to murine tissue plasminogen activator and urokinase.
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Proteases in Spinal Cord Plasticity & Regeneration
  • 批准号：
    6629430
  • 项目类别：
  • 资助金额：
    $32.19万
  • 财政年份：
    2002
  • 负责人：
    NICHOLAS W SEEDS
  • 依托单位：
    UNIVERSITY OF COLORADO DENVER
Proteases in Spinal Cord Plasticity & Regeneration
  • 批准号：
    6506070
  • 项目类别：
  • 资助金额：
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  • 财政年份：
    2002
  • 负责人：
    NICHOLAS W SEEDS
  • 依托单位：
    UNIVERSITY OF COLORADO DENVER
Proteases in Spinal Cord Plasticity & Regeneration
  • 批准号：
    8317869
  • 项目类别：
  • 资助金额：
    $17.02万
  • 财政年份：
    2002
  • 负责人：
    NICHOLAS W SEEDS
  • 依托单位：
    UNIVERSITY OF NEW MEXICO
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  • 批准号：
    6743224
  • 项目类别：
  • 资助金额：
    $32.39万
  • 财政年份：
    2002
  • 负责人：
    NICHOLAS W SEEDS
  • 依托单位：
    UNIVERSITY OF COLORADO DENVER
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