QUANTIFYING AND RELATING AGE TO AXON SPROUTING

量化年龄并将其与轴突萌发联系起来

• 批准号: 3397303
• 负责人: RICHARD E COGGESHALL
• 金额: $ 6.72万
• 依托单位: UNIVERSITY OF TEXAS MED BR GALVESTON
• 依托单位国家: 美国
• 财政年份: 1981
• 资助国家: 美国
• 起止时间: 1981-09-15 至 1988-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3397303
• 关键词: animal age group; axon; dorsal root; electron microscopy; histology; myelination; spinal cord injury; spinal cord surgery

The present proposal is designed to quantify axonal sprouting in the dorsal root and tract of Lissauer in the rat. After sprouting is quantified, the effects of age on sprouting will be determined. Rats are the experimental animal and the operative paradigms are the surviving root of Liu and Chambers and the chronic hemisection. Axons will be counted in the electron microscope which has the resolution necessary for both myelinated and unmyelinated fibers.

本建议旨在量化轴突发芽在背侧 Lissauer根和束。 在量化发芽后， 将确定年龄对发芽的影响。 老鼠是实验性的 动物和手术范式是刘慈欣生存的根本， 钱伯斯和慢性半切。 轴突将被计算在 电子显微镜，具有必要的分辨率为两个髓鞘 和无髓纤维。