Assembly, disassembly, reassembly - New Routes to Extended Structures and Their Impact

组装、拆卸、重新组装——扩展结构的新途径及其影响

• 批准号: EP/K025112/1
• 负责人: Russell Morris
• 金额: $ 163.92万
• 依托单位: University of St Andrews
• 依托单位国家: 英国
• 项目类别: Fellowship
• 财政年份: 2013
• 资助国家: 英国
• 起止时间: 2013 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=EP%2FK025112%2F1
• 关键词: Assembly; disassembly; reassembly; New; Routes

New methods for the preparation of extended structures are rightly highlighted as being of great importance to the UK. The EPSRC Grand Challenge 'Directed Assembly of Extended Structures with Targeted Properties' (referred to as the DA Grand Challenge) is championed by some of the UK's leading academic scientists. Interest from pharmaceutical companies in this initiative has been excellent, particularly based on the nucleation and crystallisation targets outlined in the Grand Challenge Documentation. Impact of the Grand Challenge Network on other areas is much less evident, although it is clear that the basic premise of the Challenge fits many other sectors. In this Established Career Proposal my vision is to demonstrate, through both transformative science and personal leadership, how the central tenets of the DA Grand Challenge Idea can be translated across disciplines. In particular I will focus on two areas, increasing the impact of the network in the chemicals sector, with a special emphasis on transformative new routes to heterogeneous zeolite catalysts (which strongly fits another EPSRC priority area), and novel multifunctionality in medical delivery agents. The proposed programme is firmly rooted in the EPSRC remit but is designed to be outward looking to maximise transdisciplinary impact cutting across to other important areas of science.The specific science proposed here focuses on nanoporous materials. Zeolites are one of the most important class of industrially applied catalysts we have. Manipulation of zeolites into hierarchical porous structures and ultra-thin layers has also risen to great prominence as a method of introducing new and beneficial features into zeolite catalysts. The journal Science rated this type of research as one of the ten most important current areas of current science, and so its importance is recognised internationally. Metal organic frameworks (MOFs) are some of the most exciting and fast-developing materials that have been prepared in the last decade or so. The great versatility of the chemistry of these solids leads to ultra-high porosity, extreme flexibility, post synthetic modification potential and many other interesting and conceivably useful attributes. Because of this wide ranging chemistry and function, potential applications of these solids range from gas storage, separation and delivery, catalysis, and sensing all the way to biology and medicine.

制备延伸结构的新方法被正确地强调为对英国非常重要。EPSRC大挑战“具有目标属性的扩展结构的定向组装”(简称DA大挑战)由英国一些领先的学术科学家倡导。制药公司对这一倡议的兴趣一直很大，特别是基于大挑战文件中概述的成核和结晶目标。大挑战网络对其他领域的影响不那么明显，尽管很明显，挑战的基本前提适用于许多其他部门。在这份既定的职业建议书中，我的愿景是通过变革性的科学和个人领导力，展示如何将发展议程大挑战理念的核心原则转化为跨学科的。我将特别关注两个领域，增加网络在化学品行业的影响，特别强调通往多相沸石催化剂的变革性新路线(这非常适合EPSRC的另一个优先领域)，以及医用递送剂中的新型多功能。拟议的计划牢牢植根于EPSRC的职权范围，但旨在向外发展，以最大限度地扩大对其他重要科学领域的跨学科影响。这里提出的具体科学集中在纳米孔材料上。沸石是工业应用催化剂中最重要的一类。沸石分子筛的分级多孔结构和超薄层的操纵也作为一种将新的和有益的特征引入沸石催化剂的方法而受到高度重视。《科学》杂志将这类研究列为当前科学的十大最重要领域之一，因此它的重要性得到了国际上的认可。金属有机骨架(MOF)是近十年来制备的最令人兴奋和发展最快的材料之一。这些固体化学的巨大多样性导致了超高的孔隙率、极高的灵活性、后合成修饰潜力和许多其他有趣的和可以想象的有用属性。由于这种广泛的化学和功能，这些固体的潜在应用范围从气体储存、分离和输送、催化和传感一直到生物和医学。

项目成果

3D to 2D Routes to Ultrathin and Expanded Zeolitic Materials

• DOI: 10.1021/cm303260z
• 发表时间: 2013-02-26
• 期刊: CHEMISTRY OF MATERIALS
• 影响因子: 8.6
• 作者: Chlubna, Pavla;Roth, Wieslaw J.;Morris, Russell E.
• 通讯作者: Morris, Russell E.

Tuning the nitric oxide release from CPO-27 MOFs.

• DOI: 10.1039/c5ra24023a
• 发表时间: 2016-02-13
• 期刊: RSC advances
• 影响因子: 3.9
• 作者: Cattaneo D;Warrender SJ;Duncan MJ;Kelsall CJ;Doherty MK;Whitfield PD;Megson IL;Morris RE
• 通讯作者: Morris RE

The assembly-disassembly-organization-reassembly mechanism for 3D-2D-3D transformation of germanosilicate IWW zeolite.

• DOI: 10.1002/anie.201400600
• 发表时间: 2014-07-01
• 期刊: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
• 影响因子: 16.6
• 作者: Chlubna-Eliasova, Pavla;Tian, Yuyang;Pinar, Ana B;Kubu, Martin;Cejka, Jiri;Morris, Russell E
• 通讯作者: Morris, Russell E

Synthesis, Isotopic Enrichment, and Solid-State NMR Characterization of Zeolites Derived from the Assembly, Disassembly, Organization, Reassembly Process.

• DOI: 10.1021/jacs.7b00386
• 发表时间: 2017-04-12
• 期刊: Journal of the American Chemical Society
• 影响因子: 15
• 作者: Bignami GPM;Dawson DM;Seymour VR;Wheatley PS;Morris RE;Ashbrook SE
• 通讯作者: Ashbrook SE

Structure and spectroscopy of hydrogen adsorbed in a nickel metal-organic framework

• DOI: 10.1016/j.chemphys.2013.08.010
• 发表时间: 2013-12-12
• 期刊: CHEMICAL PHYSICS
• 影响因子: 2.3
• 作者: Brown, Craig M.;Ramirez-Cuesta, Anibal Javier;Morris, Russell E.
• 通讯作者: Morris, Russell E.