FOURTH INTERNATIONAL SYMPOSIUM ON BIOLOGICAL REACTIVE

第四届生物反应国际研讨会

• 批准号: 3434801
• 负责人: ROBERT SNYDER
• 金额: $ 1万
• 依托单位: RUTGERS, THE STATE UNIV OF N.J.
• 依托单位国家: 美国
• 财政年份: 1989
• 资助国家: 美国
• 起止时间: 1989-07-01 至 1990-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3434801
• 关键词: adduct; alkylating agents; alkylation; cell cell interaction; chemical reaction; covalent bond; travel

The object of this proposal is to solicit funds to help support an international conference entitled THE FOURTH INTERNATIONAL SYMPOSIUM ON BIOLOGICAL REACTIVE INTERMEDIATES: MOLECULAR AND CELLULAR EFFECTS. The dates of the proposed meeting is January 14- 19, 1990, and the site will be Tucson, Arizona. The funds will be used to support travel and maintenance of both foreign and American speakers and chairpeople to Tucson where they will partake in presentations and discussions on the current state of our understanding of reactive intermediates, the chemistry of reactive species and covalent binding, DNA adduct formation and repair, immunotoxicology, oxygen, mycotoxins, pyrollizidine alkaloids, nitrosamines, hepatic and non-hepatic toxicity, and human disease related to reactive metabolites. Emphasis will be placed on the role of molecular targets (protein and DNA), and on the importance of cell-cell interactions in the development of tissue lesions. The program will include a series of invited speakers and several sessions at which volunteer presentations can be made in the form of poster sessions.

这项提议的目的是募集资金来帮助支持一个 题为第四届国际会议 生物活性中间体研讨会：分子和 细胞效应。拟召开会议的日期为1月14日- 19,1990年，地点将是亚利桑那州的图森市。这笔资金将是 用于支持外国和美国人的旅行和维护 演讲者和主席来到图森市，他们将参加 关于我们的现状的介绍和讨论 了解活性中间体、活性物质的化学 物种和共价结合，DNA加合物的形成和修复， 免疫毒理学，氧气，真菌毒素，吡咯里西丁生物碱， 亚硝胺、肝和非肝毒性与人类疾病 与反应性代谢物有关。重点将放在 分子靶标(蛋白质和DNA)的作用及其重要性 细胞间相互作用在组织损伤的发展过程中的作用。 该节目将包括一系列受邀演讲者和几位 可以通过以下形式进行志愿者介绍的会议 张贴海报的会议。