NEUROMUSCULAR FUNCTION AND DYSFUNCTION IN AGING

胃肠道运动的胃肠道相关变化没有 尽管这些变化导致了 在老年人的重大临床问题，如减少 肠道传输、便秘和肛门/直肠功能障碍。 一次讲习班 计划将审查和讨论神经， 激素、神经肽能和肌源性控制机制在 肠道正常 一系列关于生理学理论的演讲， 衰老过程中发生变化的药理学和细胞学基础 将被讨论。 研讨会的建议摘要如下： 发表在消化系统疾病和科学或 胃肠病学。 该报告的细节将提供给NIADDK， NIA和NINCDS。 研讨会计划在NIH校园举行。

Age-related changes in motility of the gastrointestinal tract have not received critical attention in spite of the fact that such changes result in significant clinical problems in the elderly such as decreased intestinal transit, constipation and anal/rectal dysfunction. A workshop is planned which will review and discuss the latest advances in neural, hormonal, neuropeptidergic and myogenic control mechanisms operative in the normal bowel. A series of presentations on theories of physiological, pharmacological and cellular basis for changes which occur during aging will be discussed. A summary of the workshop recommendations will be published either in Digestive Diseases and Sciences or in Gastroenterology. Details of the report will be made available to NIADDK, NIA and NINCDS. The workshop is planned to take place on the NIH campus.