Administrative Core

行政核心

• 批准号: 7942601
• 负责人: JOSEPH H. SZURSZEWSKI
• 金额: $ 57.56万
• 依托单位: MAYO CLINIC ROCHESTER
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-04-01 至 2015-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7942601
• 关键词: Administrative Coordination; Advisory Committees; Animal Model; Anorexia; Anorexia Nervosa; Budgets; Bulimia; Clinic; Clinical; Collaborations; Communication; Diabetes Mellitus; Disease; Eating Disorders; Ensure; Enteral; Future; Gastric Emptying; Gastrointestinal Motility; Gastrointestinal tract structure; Image; Individual; Leadership; Mails; Patients; Physiological; Preparation; Principal Investigator; Program Reviews; Research; Research Personnel; Resources; Science; Stomach; Structure; System; Telephone; Translational Research; bioimaging; cell motility; data management; experience; meetings; motility disorder; mouse model; programs

The renewal of this Program Project "Pathobiology of the Enteric System" builds upon the significant advances and accomplishments achieved during the first four years of this Program Project as well as on the extensive experience and superb record of accomplishments in the basic, clinical and translational research in gastrointestinal motility at the Mayo Clinic. This Program Project focuses on dysregulation of motility of the gastrointestinal tract in patients with diabetes and in animal models of diabetes and in mouse models of anorexia nervosa and bulimia nervosa. It expands our existing research portfolio to include research on gastric dysmotilities in these eating disorders because dysmotilities of the stomach and gastric emptying disorders seen in anorexia and bulimia nervosa mirror those seen in diabetes. This renewal request includes new staff investigators in neurogastroenterology and biomedical imaging sciences. Thus, considerable coordination and administrative effort is essential to manage this program. The Administrative Core A: (1) ensures that adequate progress is made on all projects; (2) supervises and coordinates the preparation of budgets; (3) reviews and evaluates Imaging Core B and Physiological Characterization and Data Management Core C and their resource utilization; (4) develops plans for future initiatives; (5) manages all issues and communications within relevant administrative entities at Mayo Clinic and extramurally; (6) coordinates the meetings of the Executive Committee of Administrative Core A and the Internal Advisory Committee; and (7) coordinates the annual meeting of the External Advisory Committee. Implementation and management of the Program Project will be facilitated through the leadership of the Principal Investigator, Dr. Joseph H. Szurszewski, through the Executive Committee by formal bimonthly meetings, and as needed, by telephone calls and e-mails. Assessment of scientific progress and facilitation of collaboration between the projects and cores will be accomplished through the bimonthly meetings with the Executive Committee and with the Project Leaders of the individual projects and with Directors of Imaging Core B and Physiological Characterization and Data Management Core C, review of the meetings with the Internal Advisory Committee and by annual formal review of the Program by the External Advisory Committee.

“肠道系统病理生物学”项目的续期是基于该项目前四年取得的重大进展和成就，以及梅奥诊所在胃肠运动的基础、临床和转化研究方面的丰富经验和卓越成就。本项目主要研究糖尿病患者、糖尿病动物模型以及神经性厌食症和神经性贪食症小鼠模型的胃肠道运动失调。它扩大了我们现有的研究组合，包括对这些饮食失调的胃运动障碍的研究，因为在厌食症和神经性贪食症中看到的胃运动障碍和胃排空障碍与糖尿病中看到的相似。该更新要求包括神经胃肠病学和生物医学成像科学的新工作人员调查员。因此，相当大的协调和管理工作对于管理这个项目是必不可少的。行政核心A:(1)确保所有项目取得适当进展；（二）监督、协调预算的编制；(3)综述和评价成像核心B和生理表征与数据管理核心C及其资源利用；(4)为未来的举措制定计划；(5)管理梅奥诊所内外相关行政实体内部的所有问题和沟通；(6)协调行政核心A执行委员会和内部咨询委员会的会议；(7)协调外部咨询委员会的年度会议。计划项目的实施和管理将通过首席研究员Joseph H. Szurszewski博士的领导，通过执行委员会通过正式的双月会议，必要时通过电话和电子邮件来促进。科学进展的评估和促进项目与核心之间的合作将通过与执行委员会、与单个项目的项目负责人、与成像核心B和生理表征与数据管理核心C主任的双月会议、与内部咨询委员会的会议审查以及外部咨询委员会对项目的年度正式审查来完成。