GORDON RESEARCH CONFERENCE ON MUTAGENESIS, 1992
GORDON RESEARCH CONFERENCE ON MUTAGENESIS, 1992
批准号:
3434243
负责人:
JOHN M ESSIGMANN
金额:
$0.6万
依托单位国家:
美国
项目类别:
财政年份:
1992
资助国家:
美国
项目状态:
已结题
起止时间:
1992-07-01 至 1993-06-30
中文摘要
该提案要求提供资金,以支持科学家前往
第八届两年一度的戈登突变研究会议,普利茅斯
州立大学,新罕布什尔州,1992年6月29日至7月3日。 的目的
会议将提供一个论坛,
在对诱变感兴趣的科学家中,
观点和新的想法和互动。 约135名与会者
期望来自大学、研究机构、工业和政府
世界各地的机构。 1992年会议将强调努力
为了在分子水平上理解诱变,
利用高分辨率的化学、结构、生物化学和
遗传学方法。 该计划将探讨有关的关键概念,
错误判别的结构和酶学基础,
复制、重组、转座和几个
DNA修复的类型突变,DNA如何修复的分子细节
损伤被加工成突变,几个专门的突变
对生存至关重要的过程,以及人类基因突变的基础
遗传疾病,包括癌症。 阐明突变机制是
对于理解各种有害的
以及遗传信息改变的有益后果。
英文摘要
This proposal requests funds to support the travel of scientists to the
eighth biannual Gordon Research Conference on Mutagenesis, at Plymouth
State College, New Hampshire, on June 29-July 3, 1992. The purpose of
the conference is to provide a forum for presentations by and discussions
among scientists interested in mutagenesis, in order to generate fresh
perspectives and new ideas and interactions. About 135 attendees are
expected from universities, research institutes, industry and government
agencies around the world. The 1992 Conference will emphasize attempts
to understand mutagenesis at the molecular level by focusing on recent
progress using highresolution chemical, structural, biochemical and
genetical approaches. The program will explore key concepts relating to
the structural and enzymological basis of error discrimination, the
relationship among replication, recombination, transposition and several
types of DNA repair to mutagenesis, the molecular details of how DNA
damage is processed into mutations, several specialized mutational
processes critical for survival, and the mutational basis of human
genetic diseases, including cancer. Elucidating mutational mechanisms is
of fundamental importance for understanding a variety of both deleterious
and beneficial consequences of alterations in genetic information.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Project 2: High Resolution Mutation Spectra and Multi-Omics for Deducing Etiology and Predicting Disease
-
批准号:10351933
-
项目类别:
-
资助金额:$52.07万
-
财政年份:2017
-
负责人:JOHN M ESSIGMANN
-
依托单位:
Core D: Research Experience and Training Coordination Core
-
批准号:10688032
-
项目类别:
-
资助金额:$6.14万
-
财政年份:2017
-
负责人:JOHN M ESSIGMANN
-
依托单位:
Core D: Research Experience and Training Coordination Core
-
批准号:10351939
-
项目类别:
-
资助金额:$6.35万
-
财政年份:2017
-
负责人:JOHN M ESSIGMANN
-
依托单位:
Science and Engineering for Sensors, Mechanisms, and Biomarkers of Exposures
-
批准号:9259573
-
项目类别:
-
资助金额:$125.9万
-
财政年份:2017
-
负责人:JOHN M ESSIGMANN
-
依托单位:
Project 2: High Resolution Mutation Spectra and Multi-Omics for Deducing Etiology and Predicting Disease
-
批准号:10687979
-
项目类别:
-
资助金额:$48.05万
-
财政年份:2017
-
负责人:JOHN M ESSIGMANN
-
依托单位:
The Environment as a Variable to Calibrate Mouse Models of Human Disease
-
批准号:7351205
-
项目类别:
-
资助金额:$54.44万
-
财政年份:2008
-
负责人:JOHN M ESSIGMANN
-
依托单位:
The Environment as a Variable to Calibrate Mouse Models of Human Disease
-
批准号:8577178
-
项目类别:
-
资助金额:$31.59万
-
财政年份:2008
-
负责人:JOHN M ESSIGMANN
-
依托单位:
The Environment as a Variable to Calibrate Mouse Models of Human Disease
-
批准号:8727548
-
项目类别:
-
资助金额:$31.27万
-
财政年份:2008
-
负责人:JOHN M ESSIGMANN
-
依托单位:
The Environment as a Variable to Calibrate Mouse Models of Human Disease
-
批准号:8212454
-
项目类别:
-
资助金额:$56.54万
-
财政年份:2008
-
负责人:JOHN M ESSIGMANN
-
依托单位:
The Environment as a Variable to Calibrate Mouse Models of Human Disease
-
批准号:8895929
-
项目类别:
-
资助金额:$31.59万
-
财政年份:2008
-
负责人:JOHN M ESSIGMANN
-
依托单位:
The Environment as a Variable to Calibrate Mouse Models of Human Disease
-
批准号:8005036
-
项目类别:
-
资助金额:$56.54万
-
财政年份:2008
-
负责人:JOHN M ESSIGMANN
-
依托单位:
The Environment as a Variable to Calibrate Mouse Models of Human Disease
-
批准号:8097655
-
项目类别:
-
资助金额:$8.5万
-
财政年份:2008
-
负责人:JOHN M ESSIGMANN
-
依托单位:
The Environment as a Variable to Calibrate Mouse Models of Human Disease
-
批准号:7546585
-
项目类别:
-
资助金额:$55.52万
-
财政年份:2008
-
负责人:JOHN M ESSIGMANN
-
依托单位:
GENOTOXICITY OF CISPLATIN, A PLEIOTROPIC TOXIN
-
批准号:6127865
-
项目类别:
-
资助金额:$28.99万
-
财政年份:2000
-
负责人:JOHN M ESSIGMANN
-
依托单位:
Mechanistic Comparison of Cisplatin with Synthetic DNA Repair-Shielding Anticance
-
批准号:7142123
-
项目类别:
-
资助金额:$29.11万
-
财政年份:2000
-
负责人:JOHN M ESSIGMANN
-
依托单位:
Mechanistic Comparison of Cisplatin with Synthetic DNA Repair-Shielding Anticance
-
批准号:7495925
-
项目类别:
-
资助金额:$5.32万
-
财政年份:2000
-
负责人:JOHN M ESSIGMANN
-
依托单位:
Mechanistic Comparison of Cisplatin with Synthetic DNA Repair-Shielding Anticance
-
批准号:7423986
-
项目类别:
-
资助金额:$28.26万
-
财政年份:2000
-
负责人:JOHN M ESSIGMANN
-
依托单位:
Mechanistic Comparison of Cisplatin with Synthetic DNA Repair-Shielding Anticance
-
批准号:7629169
-
项目类别:
-
资助金额:$22.94万
-
财政年份:2000
-
负责人:JOHN M ESSIGMANN
-
依托单位:
GENOTOXICITY OF CISPLATIN, A PLEIOTROPIC TOXIN
-
批准号:6514495
-
项目类别:
-
资助金额:$29.33万
-
财政年份:2000
-
负责人:JOHN M ESSIGMANN
-
依托单位:
Mechanistic Comparison of Cisplatin with Synthetic DNA Repair-Shielding Anticance
-
批准号:7840479
-
项目类别:
-
资助金额:$28.26万
-
财政年份:2000
-
负责人:JOHN M ESSIGMANN
-
依托单位:
海外基金