Flexible Single-Optical-Fibre Endoscope

柔性单光纤内窥镜

基本信息

  • 批准号:
    EP/L022559/2
  • 负责人:
  • 金额:
    $ 9.22万
  • 依托单位:
  • 依托单位国家:
    英国
  • 项目类别:
    Research Grant
  • 财政年份:
    2015
  • 资助国家:
    英国
  • 起止时间:
    2015 至 无数据
  • 项目状态:
    已结题

项目摘要

Recently, researchers at Massachusetts Institute of Technology and Korean University demonstrated a single multimode-optical-fibre (MMF) imaging endoscope. Compared with conventional fibre-bundle based endoscopes, this device is ultra-slim, high-resolution, wide-field, lensless, low cost and disposable. The main drawback of such devices is that they cannot be used as flexible endoscopes due to image blurring caused by fibre-shape variation. However, flexible endoscopes are viewed as most desirable and are widely used in modern healthcare. In order to overcome this problem, this research aims to develop the world's first flexible single-fibre endoscope system by using a novel speckle monitoring technique. The monitoring module will consist of a calibration beam and associated optics to monitor the real-time changes in mode coupling induced by fibre movement and bending. The monitoring results will be used to predict MMF imaging transmission matrix for original image restoration. At the end of the project, a prototype device together with real-time software and algorithms will be developed for potential clinical trials and translational research. The project is highly interdisciplinary: it brings together expertise in the areas of optics, instrumentation, imaging, signal processing and surgery. The outcome of the proposed research has the potential to put the UK at the forefront of a crucial emerging area of new medical devices for modern endoscopy, which is likely to have a huge impact not only on research and patient well-being, but also on the UK and global economy.
最近,马萨诸塞州理工学院和韩国大学的研究人员展示了一种单一的多模光纤(MMF)成像内窥镜。与传统的光纤束内窥镜相比,该设备具有超薄、高分辨率、宽视场、无透镜、低成本和一次性使用等优点。这种装置的主要缺点是,由于纤维形状变化引起的图像模糊,它们不能用作柔性内窥镜。然而,柔性内窥镜被认为是最理想的,并广泛用于现代医疗保健。为了克服这一问题,本研究的目的是开发世界上第一个灵活的单纤维内窥镜系统,通过使用一种新的散斑监测技术。监测模块将由校准光束和相关光学器件组成,以监测由光纤移动和弯曲引起的模式耦合的实时变化。监测结果将用于预测MMF成像传输矩阵,以恢复原始图像。在项目结束时,将开发一个原型设备以及实时软件和算法,用于潜在的临床试验和转化研究。该项目是高度跨学科的:它汇集了光学,仪器,成像,信号处理和手术领域的专业知识。拟议研究的结果有可能使英国处于现代内窥镜新医疗设备的关键新兴领域的最前沿,这不仅可能对研究和患者福祉产生巨大影响,而且可能对英国和全球经济产生巨大影响。

项目成果

期刊论文数量(10)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Tuning parameters of phase retrieval algorithm for single-shot imaging based on object-modulated speckles by particle swarm optimization
  • DOI:
    10.1016/j.optlastec.2022.109004
  • 发表时间:
    2023
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Cesar Arturo Hernandez-Alvarez;Lipei Song;Yufei Wang;T. Alonso-Rasgado;Lei Su
  • 通讯作者:
    Cesar Arturo Hernandez-Alvarez;Lipei Song;Yufei Wang;T. Alonso-Rasgado;Lei Su
Light Propagation Prediction through Multimode Optical Fibers with a Deep Neural Network
使用深度神经网络预测通过多模光纤的光传播
  • DOI:
    10.1109/iaeac.2018.8577930
  • 发表时间:
    2018
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Fan P
  • 通讯作者:
    Fan P
Deep Learning Enabled Scalable Calibration of a Dynamically Deformed Multimode Fiber
深度学习实现动态变形多模光纤的可扩展校准
Learning Enabled Continuous Transmission of Spatially Distributed Information through Multimode Fibers
  • DOI:
    10.1002/lpor.202000348
  • 发表时间:
    2021-02-24
  • 期刊:
  • 影响因子:
    11
  • 作者:
    Fan, Pengfei;Ruddlesden, Michael;Su, Lei
  • 通讯作者:
    Su, Lei
C-shape microfiber taper interferometer for simultaneous measurement of curvature and temperature
C型微纤维锥度干涉仪,可同时测量曲率和温度
  • DOI:
    10.1016/j.ijleo.2017.07.014
  • 发表时间:
    2017-09
  • 期刊:
  • 影响因子:
    3.1
  • 作者:
    Haimei Luo;Lei Su;Jinshuai Zhang;Wen Yuan;Sheng Liu;Yifan Wang;Changjing Wang;Xianping Wang
  • 通讯作者:
    Xianping Wang
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Lei Su其他文献

Cross-domain question classification in community question answering via kernel mapping
通过内核映射进行社区问答中的跨域问题分类
Radiation Effects in the Crystalline-Amorphous SiOC Polymer-Derived Ceramics: Insights from Experiments and Molecular Dynamics Simulation
结晶非晶 SiOC 聚合物衍生陶瓷中的辐射效应:实验和分子动力学模拟的见解
  • DOI:
    10.1021/acsami.1c10917
  • 发表时间:
    2021
  • 期刊:
  • 影响因子:
    9.5
  • 作者:
    Min Niu;Hongfei Gao;Zihao Zhao;Hongjie Wang;Lei Su;Lei Zhuang;Shuhai Jia;Alex;ra Navrotsky
  • 通讯作者:
    ra Navrotsky
Su1780 Eicosapentaenoic Acid Enhances Heat Stress-Impaired Intestinal Epithelial Barrier Function in Caco-2 Cells
Su1780 二十碳五烯酸增强 Caco-2 细胞中热应激损伤的肠上皮屏障功能
  • DOI:
  • 发表时间:
    2013-05
  • 期刊:
  • 影响因子:
    29.4
  • 作者:
    Gui-Zhen Xiao;Li-Qun Tang;Fang-Fang Yuan;Zhi-Feng Liu;Ya-Li Zhang;Lei Su
  • 通讯作者:
    Lei Su
Amplifed antitumor efficacy by a targeted drug retention and chemosensitization strategy-based “combo” nanoagent together with PD-L1 blockade in reversing multidrug resistance
通过基于靶向药物保留和化疗增敏策略的“组合”纳米药物与 PD-L1 阻断结合逆转多药耐药性,增强抗肿瘤功效
  • DOI:
  • 发表时间:
    2021
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Weixi Jiang;Lei Su;Meng Ao;Xun Guo;Chen Cheng;Yuanli Luo;Zhuoyan Xie;Xingyue Wang;Junrui Wang;Shuling Liu;Yang Cao;Pan Li;Zhigang Wan;Haitao Ran;Zhiyi Zhou;Jianli Ren (共同通讯作者)
  • 通讯作者:
    Jianli Ren (共同通讯作者)
Experimental investigation on dynamic characteristics of sandy gravel in frozen region
冻区砂砾石动力特性试验研究
  • DOI:
    10.1016/j.coldregions.2021.103251
  • 发表时间:
    2021-05
  • 期刊:
  • 影响因子:
    4.1
  • 作者:
    Fada Li;Lei Su;Huaping Wan;Fujun Niu;Xianzhang Ling
  • 通讯作者:
    Xianzhang Ling

Lei Su的其他文献

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{{ truncateString('Lei Su', 18)}}的其他基金

Wafer-Scale Manufacturing of Single-Crystal Perovskite Optoelectronics
单晶钙钛矿光电器件的晶圆级制造
  • 批准号:
    EP/V050311/1
  • 财政年份:
    2021
  • 资助金额:
    $ 9.22万
  • 项目类别:
    Research Grant
Body-Worn Sensor for Point-of-Care Vascular Access Monitoring
用于护理点血管通路监测的穿戴式传感器
  • 批准号:
    EP/W004399/1
  • 财政年份:
    2021
  • 资助金额:
    $ 9.22万
  • 项目类别:
    Research Grant
Flexible Single-Optical-Fibre Endoscope
柔性单光纤内窥镜
  • 批准号:
    EP/L022559/1
  • 财政年份:
    2014
  • 资助金额:
    $ 9.22万
  • 项目类别:
    Research Grant

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用于单个小细胞外囊泡分析的光学超表面
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