SENSITIVE PROBE FOR INTRA-OPERATIVE BONE SCANNING
SENSITIVE PROBE FOR INTRA-OPERATIVE BONE SCANNING
批准号:
3490206
负责人:
GERALD ENTINE
金额:
$5.0万
依托单位国家:
美国
项目类别:
财政年份:
1985
资助国家:
美国
项目状态:
已结题
起止时间:
1985-07-01 至 1985-12-14
中文摘要
成功治疗骨病最关键的考虑因素之一
肿瘤和感染是在手术过程中发现和定位的。
尽管核医学扫描技术是一种被广泛接受的
有效的成像方法,它们很难在紧凑的地方使用
手术室的范围。
这一限制在删除广泛的种类时尤其重要
指感染组织很少或没有显示出解剖结构的骨损伤
反常现象。在几乎所有这些案例中,定义
病变的边界导致切除过多的或
组织太少,导致随之而来的临床后果。
最近的临床实验表明,一种敏感的、手持的、
核探针可能对定位骨骼病变有很大帮助
在手术期间。RMD,Inc.与皇后医疗中心合作
罗切斯特大学医学中心建议进行这项研究
有必要开发一种极其灵敏的、微型的仪器
术中骨扫描。这种新的手持设备将允许
外科医生在活组织检查或治疗期间准确定位肿瘤或病变组织
并为手术成功提供了一种非常有价值的技术
治疗这类严重的骨病。
英文摘要
One of the most critical considerations in the successful treatment of bone
tumors and infections is their detection and localization during surgery.
Although nuclear medicine scanning techniques are a widely accepted and
effective approach for imaging, they are very difficult to use in the tight
confines of the operating room.
This limitation is particularly important in the removal of a wide variety
of bone lesions in which the infected tissue shows little or no anatomical
abnormality. In virtually all of these cases, the difficulty in defining
the boundaries of the lesions result in the removal of either too much or
too little tissue and causes the attendant clinical consequences.
Recent clinical experiments have indicated that a sensitive, hand held,
nuclear probe could be of great assistance in localizing bone lesions
during surgery. RMD, Inc. in collaboration with Queen's Medical Center and
the University of Rochester Medical Center, proposes to do the research
necessary to develop an extremely sensitive, miniaturized instrument for
intra-operative bone scanning. This new hand held device will allow
surgeons to accurately locate tumorous or diseased tissue during biopsy or
resection and provide a very valuable technique for the successful
treatment of this serious class of bone diseases.
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