Simultaneous PET-MR Small Animal Imaging

同步 PET-MR 小动物成像

基本信息

  • 批准号:
    7906390
  • 负责人:
  • 金额:
    $ 14.94万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2010
  • 资助国家:
    美国
  • 起止时间:
    2010-03-15 至 2011-02-28
  • 项目状态:
    已结题

项目摘要

DESCRIPTION (provided by applicant): Simultaneous PET-MR Small Animal Imaging Principal Investigator: Dr. Gerald Entine, Ph.D. Abstract: The ideal biological imaging system would provide non-invasive, high-resolution, high-sensitivity, three-dimensional (3D) images of living systems. Positron Emission Tomography (PET) offers high sensitivity to a range of biological processes through the use of targeted radio labeled probes. Unfortunately, precise signal localization can be extremely difficult due to low spatial resolution and the lack of anatomical information. Magnetic Resonance Imaging (MRI) can provide high spatial resolution and excellent soft tissue contrast, but suffers from poor signal strength leading to low sensitivity. The overall goal of the proposed effort is to combine the best features of PET and MR modalities for small animal studies into a single, very high performance imaging instrument that will record data in both imaging modalities simultaneously. The most obvious benefit of the integrated system will be to provide high-resolution anatomical context for small-animal PET studies. This will lead to better overall understanding of the origin of the PET signals. The 'in-register' MR images can be used to estimate partial volume errors in the lower-resolution PET scans, thus aiding quantification of the PET signal. To achieve these objectives, a high resolution, high sensitivity PET system will be designed and built and will be tested first on a bench, followed by detailed evaluation inside a commercial small animal MR imaging system.
描述(由申请人提供):同步PET-MR小动物成像主要研究者:Gerald Entine博士,Ph.D。

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

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GERALD ENTINE其他文献

GERALD ENTINE的其他文献

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{{ truncateString('GERALD ENTINE', 18)}}的其他基金

Low Cost Photon Counting Detector for Synchrotron Applications
适用于同步加速器应用的低成本光子计数探测器
  • 批准号:
    7801181
  • 财政年份:
    2010
  • 资助金额:
    $ 14.94万
  • 项目类别:
Near Infrared Detector for Advanced Opthamology
用于高级眼科的近红外探测器
  • 批准号:
    7536348
  • 财政年份:
    2008
  • 资助金额:
    $ 14.94万
  • 项目类别:
High Resolution Detectors for Single Photon Cardiac Imaging
用于单光子心脏成像的高分辨率探测器
  • 批准号:
    7536797
  • 财政年份:
    2008
  • 资助金额:
    $ 14.94万
  • 项目类别:
High Resolution Detectors for Single Photon Cardiac Imaging
用于单光子心脏成像的高分辨率探测器
  • 批准号:
    7908907
  • 财政年份:
    2008
  • 资助金额:
    $ 14.94万
  • 项目类别:
High Resolution Detectors for Single Photon Cardiac Imaging
用于单光子心脏成像的高分辨率探测器
  • 批准号:
    7700096
  • 财政年份:
    2008
  • 资助金额:
    $ 14.94万
  • 项目类别:
Solid-State Photosensor for PET
PET 固态光电传感器
  • 批准号:
    7325545
  • 财政年份:
    2007
  • 资助金额:
    $ 14.94万
  • 项目类别:
HIGH RESOLUTION NUCLEAR CARDIAC IMAGING
高分辨率核心脏成像
  • 批准号:
    7470656
  • 财政年份:
    2007
  • 资助金额:
    $ 14.94万
  • 项目类别:
Position Sensitive Microfluidic Detector
位置敏感微流控探测器
  • 批准号:
    7404768
  • 财政年份:
    2007
  • 资助金额:
    $ 14.94万
  • 项目类别:
HIGH RESOLUTION NUCLEAR CARDIAC IMAGING
高分辨率核心脏成像
  • 批准号:
    7270088
  • 财政年份:
    2007
  • 资助金额:
    $ 14.94万
  • 项目类别:
HIGH RESOLUTION NUCLEAR CARDIAC IMAGING
高分辨率核心脏成像
  • 批准号:
    7050314
  • 财政年份:
    2006
  • 资助金额:
    $ 14.94万
  • 项目类别:

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