Chronic active viral persistence versus host immune mediated pathology: an analysis and manipulation of the balance.
Chronic active viral persistence versus host immune mediated pathology: an analysis and manipulation of the balance.
批准号:
nhmrc : 1006592
负责人:
Prof Marc Pellegrini
金额:
$27.92万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2011
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2011-01-01 至 2013-12-31
中文摘要
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英文摘要
Our robust ability to mount an immune response and clear infections is tempered by the possibility of promoting autoimmunity. Several host genes regulate immunity. Viruses like HIV have exploited these to abrogate antiviral immunity. This project attempts to define host factors that promote chronic infection. This will be extremely valuable in understanding the vulnerabilities of our immune system and provide an insight into how we can treat chronic infections.
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依托单位:
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