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Targeting host pathogen interactions and signalling networks to promote death of infected cells and facilitate pathogen clearance

Targeting host pathogen interactions and signalling networks to promote death of infected cells and facilitate pathogen clearance
针对宿主病原体相互作用和信号网络,促进受感染细胞死亡并促进病原体清除
批准号:
nhmrc : 1078186
负责人:
Prof Marc Pellegrini
金额:
$0.0万
依托单位国家:
澳大利亚
项目类别:
Research Fellowships
财政年份:
2015
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2015-01-01 至 2019-12-31

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中文摘要
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英文摘要
Preclinical models of infectious diseases including hepatitis B, HIV, tuberculosis and human herpes virus infections will be used to understand how pathogens interact with host cells. With this understanding we aim to identify which host cell signalling pathways play a critical role in limiting or faciliating pathogen persistence. After identifying the important cellular pathways we aim to target these host cell signalling components with clinical stage drugs to promote pathogen clearance.
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New drug combinations to enhance elimination of hepatitis B infection
Targeting host pathogen interactions and signalling networks to promote death of infected cells and facilitate pathogen clearance
  • 批准号:
    nhmrc : GNT1078186
  • 项目类别:
    Research Fellowships
  • 资助金额:
    $61.16万
  • 财政年份:
    2015
  • 负责人:
    Prof Marc Pellegrini
  • 依托单位:
The role of Rip3 and caspase 8 in necroptosis and apoptosis during viral infection
Understanding the role of host Arih2 in defence against viral infection and disease pathogenesis
国内基金
海外基金
lncRNA-HOST2—USP15—VGLL4轴促进乳腺癌肝转移的机制研究
  • 批准号:
    82073204
  • 项目类别:
    面上项目
  • 资助金额:
    55.0万元
  • 批准年份:
    2020
  • 负责人:
    房林
  • 依托单位:
新鉴定PA-X“host-shutoff”功能区调控H7N9禽流感病毒毒力的机制
  • 批准号:
    32072832
  • 项目类别:
    面上项目
  • 资助金额:
    58.0万元
  • 批准年份:
    2020
  • 负责人:
    胡娇
  • 依托单位:
能量代谢触发植入干细胞和损伤视网膜细胞Graft-to Host细胞间通讯/物质交换及命运转变的机制
溶液加工型多层磷光器件的组装与性能优化