Clinical and psychosocial changes over late childhood and adolescence and early life determinants of long term clinical outcomes in cystic fibrosis

童年晚期和青春期的临床和社会心理变化以及囊性纤维化长期临床结果的早期生活决定因素

• 批准号: nhmrc : GNT1044829
• 负责人: A/Pr Geraint Rogers
• 金额: $ 75.72万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/clinical-psychosocial-changes-cystic-fibrosis/1344450
• 关键词: Clinical; psychosocial; changes; over; late

Cystic fibrosis is the most common life shortening inherited disease in Caucasians. Lung damage starts in infancy and lung function falls most rapidly in adolescence although why and how this happens and early life determinants are not known. This study takes advantage of a previous study that monitored young children from 3 months to 5 years of life and follows them closely through early adolescence to investigate the protective and risk factors for falling lung function.

囊性纤维化是高加索人最常见的缩短寿命的遗传性疾病。肺损伤从婴儿期开始，肺功能在青春期下降最快，尽管为什么和如何发生这种情况以及早期生活的决定因素尚不清楚。这项研究利用了之前的一项研究，该研究对3个月至5岁的幼儿进行了监测，并在青春期早期对他们进行了密切跟踪，以调查肺功能下降的保护性因素和风险因素。