COLLAGENATED SILICONE IPN-BASED BURN DRESSING

本研究项目的目的是论证其可行性 利用一系列新开发的微孔膜治疗烧伤 穿衣应用程序。有机硅基互穿聚合物网络 (“IPN”)已经被开发出来，并且微孔膜能够 在一侧涂覆有交联型胶原网络和 糖胺多聚糖。水蒸气透过率 透明的IPN可精确控制；此外，材料 有效的细菌屏障，手感或悬垂性极佳 特点。本项目将具体探讨其可行性。 使用这种膜作为可生物降解材料的支撑基质 透明烧伤敷料的蛋白质层。 长期目标：提供新的烧伤敷料材料 评估其他医疗应用 方法：制作薄膜样品 评估生产方法 体外表征 原型生产 技术创新：新开发的生物相容性互穿网络 复合样式属性 可控式录像机

The objective of this research project is to demonstrate the feasibility of utilizing a newly developed family of microporous membranes for burn dressing applications. A silicone based interpenetrating polymer network ("IPN") has been developed, and the microporous membrane is capable of being coated on one side with a crosslinked network of collagen and glycosaminoglycan. The moisture vapor transmission rate of the transparent IPN can be precisely controlled; furthermore, the material is an effective bacteria barrier and has excellent hand or drapability characteristics. This project will specifically explore the feasibility of using such membranes as a supportive matrix for the biodegradable protein layer of a transparent burn dressing. Long term objectives: Provide new burn dressing material Evaluate other medical applications Methodology: Produce membrane samples Evaluate production methodology In vitro characterization Prototype production Technological Innovation: Newly developed biocompatible IPN Composite style properties Controllable MVTR