NOVEL VASCULAR PROSTHETIC DEVICE

这项研究项目的目的是论证 新型微孔材料在血管假体中的应用 并研究了各种工艺参数和它们的应用 对最终产品的物理性能的影响。一种相互渗透的 聚四氟乙烯(PTFE)聚合物网络(IPN)和 聚二甲基硅氧烷(PDMS)是使用拉伸方法来膨胀的，该拉伸方法 结果形成了微孔结构。方法将包括混合， 预成型、挤压、膨胀和烧结。这个项目是 技术上的创新，因为IPN组合物在几个方面都是新颖的 敬重。PTFE/PDMS IPN能够像普通PTFE一样扩展， 然而，形态、表面化学和物理完整性都是非典型的。 这些独特的特征被认为非常适合于一般 血管假体的应用，并可能为 更困难的目标应用，如小直径假体。

The objective of this research project is to demonstrate the feasibility of utilizing a newly developed microporous material for vascular prosthetic applications, and also to study the various process parameters and their effect on the physical properties of the end product. An interpenetrating polymer network ("IPN") of polytetrafluoroethylene ("PTFE") and polydimethylsiloxane ("PDMS") is expanded using a stretching process which results in a microporous structure. Methodology will include blending, preforming, extrusion, expansion and sintering. This project is technologically innovative because the IPN composition is novel in several respects. PTFE/PDMS IPNs are capable of being expanded like ordinary PTFE, yet morphology, surface chemistry and physical integrity are atypical. These unique characteristics are believed to be well suited for general vascular prosthetic applications, and may offer discrete advantages for more difficult target applications such as small diameter prostheses.