AUDITORY BRAINSTEM RESPONSE AT HIGH STIMULUS RATES

高刺激率下的听觉脑干反应

• 批准号: 3494652
• 负责人: BARBARA SILVERBERG
• 金额: $ 5万
• 依托单位: ABRATECH CORPORATION
• 依托单位国家: 美国
• 财政年份: 1989
• 资助国家: 美国
• 起止时间: 1989-01-01 至 1989-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3494652
• 关键词: auditory pathways; auditory stimulus; brain stem; cats; clinical biomedical equipment; computer assisted diagnosis; diagnosis design /evaluation; evoked potentials; stimulus /response; stimulus interval

The goal of this research is to implement and test an algorithm that will permit accurate recording of the Auditory Brainstem Response (ABR) at very high repetition rates, by extracting the ABR from later responses (e.g., the Middle Latency Response -- MLR). Phase I will accomplish the goal of programming the necessary stimulus and analysis algorithms, and will test the method under conditions of real noise and jitter by analyzing ABR recordings from anesthetized laboratory cats. Phase II will study the use of the method in recordings from humans, using a variety of filter settings and three or more simultaneous channels. The improved method of recording the ABR will increase the sensitivity of ABR testing in a wide variety of diseases, including HIV infection and AIDS.

这项研究的目标是实现和测试算法 这将允许准确记录听觉脑干 通过提取 ABR，以非常高的重复率获得响应 (ABR) 来自后来的响应（例如，中延迟响应 - MLR）。 第一阶段将实现对必要的程序进行编程的目标 刺激和分析算法，并将在下测试该方法 通过分析 ABR 录音来了解真实噪声和抖动的情况 来自麻醉的实验室猫。 第二阶段将研究使用 该方法来自人类的录音，使用各种过滤器 设置和三个或更多同步通道。 改进的ABR记录方法将增加 ABR 检测对多种疾病的敏感性，包括 艾滋病毒感染和艾滋病。

项目成果

Role of the amygdala complex in early olfactory associative learning.

杏仁核复合体在早期嗅觉联想学习中的作用。

• DOI: 10.1037//0735-7044.107.2.254
• 发表时间: 1993
• 期刊: Behavioral neuroscience
• 影响因子: 1.9
• 作者: Sullivan,RM;Wilson,DA
• 通讯作者: Wilson,DA