A NEUROMUSCULAR BLOCKADE MONITOR USING PIEZOELELECTRIC M

使用压电 M 的神经肌肉阻断监视器

• 批准号: 3504546
• 负责人: DWAYNE R WESTENSKOW
• 金额: $ 5万
• 依托单位: ROCKY MOUNTAIN RESEARCH, INC.
• 依托单位国家: 美国
• 财政年份: 1991
• 资助国家: 美国
• 起止时间: 1991-05-15 至 1991-11-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3504546
• 关键词: anesthesia; biosensor device; clinical biomedical equipment; neuromuscular function; neuromuscular stimulator; paralysis; patient monitoring device

There is a growing need to better monitor neuromuscular blockage during and immediately after anesthesia. Experts state that the only reliable method of monitoring neuromuscular function is by stimulating a peripheral nerve and measuring the evoked response of a skeletal muscle. Neuromuscular monitoring helps the anesthesiologist with a more predictable and rational approach to the use of muscle relaxants, and hence in better patient care. Monitoring measures whether a patient is adequately paralyzed during surgery, and if he will be capable of breathing on his own after surgery is over. We plan to develop a handheld neuromuscular monitor to be used in the operating room. The monitor will deliver an electrical stimulus under computer control and will measure the patient's resultant muscle movement with a piezo-film sensor. the disposable, proprietary motion sensor conveniently attaches to the patient, making the unit much easier to use than currently available monitors. After completion of the prototype, it will be tested clinically in 10 patients to compare its accuracy with a standard measurement system. The ease of application gives considerable advantage to the motion sensor over currently available techniques, making it the preferred method of monitoring neuromuscular relaxation.

越来越需要更好地监测神经肌肉阻滞， 麻醉后立即 专家指出，唯一可靠的方法 是通过刺激周围神经 以及测量骨骼肌的诱发反应。 神经肌肉 监测有助于麻醉师更可预测和合理地 使用肌肉松弛剂的方法，从而更好地护理病人。 监测措施是否病人充分瘫痪， 手术，如果他能在手术后自己呼吸， 结束了 我们计划开发一种手持式神经肌肉监测仪， 手术室 监视器会在一定的电压下 计算机控制，并将测量患者的肌肉运动 压电薄膜传感器。 一次性专利运动传感器 方便地连接到病人，使单位更容易使用 比目前可用的监视器。 原型完成后， 将在10名患者中进行临床测试，以比较其准确性， 标准测量系统 应用程序的易用性提供了相当大的 运动传感器相对于当前可用技术的优点， 它是监测神经肌肉松弛的优选方法。

项目成果

A comparison of dynamic and isometric force sensors for train-of-four measurement using submaximal stimulation current.

使用次最大刺激电流进行四列测量的动态力传感器和等距力传感器的比较。

• DOI: 10.1007/bf01627415
• 发表时间: 1995
• 期刊: Journal of clinical monitoring
• 作者: Kern,SE;Johnson,JO;Westenskow,DR;Orr,JA
• 通讯作者: Orr,JA

An effectiveness study of a new piezoelectric sensor for train-of-four measurement.

用于四列测量的新型压电传感器的有效性研究。

• DOI: 10.1213/00000539-199405000-00025
• 发表时间: 1994
• 期刊: Anesthesia and analgesia
• 影响因子: 5.7
• 作者: Kern,SE;Johnson,JO;Westenskow,DR;Orr,JA
• 通讯作者: Orr,JA