SOLID STATE LASER FOR VASCULAR LESION TREATMENT

描述（改编自申请人的摘要）：前列腺癌的治疗 色斑、毛细血管扩张和其他皮肤微血管畸形 已经被激光手术大大改善了。 1981- 1983年间， 安德森和他的同事们发现了一种叫做“选择性”的方法 光疗”，这导致有效但基本上无疤痕 治疗。 这种方法后来得到了改进，现在是一种成熟的， 在皮肤科中被广泛接受且基本上是独特的治疗方法。 目前，最能满足工业要求的激光系统 治疗是长脉冲染料激光器，工作波长为585 nm， 可见光谱中的黄色区域。 存在许多问题 涉及染料激光器的操作特性和使用。在 第一阶段的建议，调查者的计划，调查的发展， 一种固态激光系统，将取代现有的激光器， 一些染料激光器的问题 一种改进的黄色光源 可以使血管病变治疗更广泛地获得， 成本

DESCRIPTION (Adapted from applicant's abstract):The treatment of portwine stains, telangiectases and other microvascular malformations of the skin has been greatly improved by laser surgery. Between 1981-83, work by Anderson and colleagues identified an approach called "selective photothermolysis", which led to effective yet essentially non-scarring treatments. This approach has since been refined and is now a mature, well-accepted, and essentially unique treatment in dermatology. At present, the laser system best satisfying the requirements of the treatment is a long-pulse dye laser, operating at a wavelength of 585 nm, the yellow region of the visible spectrum. There are a number of problems related to the operating characteristics and use of the dye laser. In the Phase I proposal, the investigator's plan to investigate the development of a solid state laser system that would replace current lasers and eliminate some, if not all of the dye-laser problems. An improved yellow source could make vascular-lesion treatment more widely available and lower in cost.