SINGLE-CRYSTAL POSITRON TOMOGRAPH

单晶正电子断层扫描

• 批准号: 3509220
• 负责人: GERD MUEHLLEHNER
• 金额: $ 24.71万
• 依托单位: UGM MEDICAL SYSTEMS, INC.
• 依托单位国家: 美国
• 财政年份: 1988
• 资助国家: 美国
• 起止时间: 1988-09-01 至 1991-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3509220
• 关键词: clinical biomedical equipment; crystallization; iodine; positron emission tomography; radionuclide diagnosis; sodium

Positron emission tomography (PET) has been shown to be useful in the diagnosis of a wide variety of neurological and cardiac diseases. For neurological imaging, dedicated brain scanners have the advantages of increased sensitivity and better spatial resolution due to their reduced apterture size and detector separation. We propose the design and construction of a prototype dedicated brain scanner which will have significant advantages for clinical neurological imaging. The scanner is based on the use of a detector composed of a single, continuous cylindrical NaI(T1) crystal. This crystal, 65 cm in diameter and 21 cm in its axial extent, would be coupled to approximately 160 photomultipliers to yield a tomographic with a useful axial field-of- view of at least 12 cm and 2 mm data sampling along all three image axes. The use of a single NaI(T1) crystal results not only in dramatically reduced system complexity and cost, but also in good spatial, timing, and energy resolution. In Phase I of the project, the feasibility of manufacturing the cylindrical crystal and of detecting coincidences in a single continuous crystal were demonstrated. In Phase II, we intend to construct and test a prototype of the single-crystal tomograph.

正电子发射断层扫描（PET）已被证明是有用的， 诊断各种神经和心脏疾病。 为 神经成像，专用脑部扫描仪具有以下优点： 提高灵敏度和更好的空间分辨率， 孔径大小和探测器间距。 我们建议设计和建造一个专用大脑的原型 扫描仪，这将有显着的优势，临床神经 显像 该扫描仪是基于使用一个探测器组成的一个 单个连续圆柱形NaI（T1）晶体。 这块65厘米长的水晶 直径和21厘米，在其轴向范围内，将耦合到大约 160个光电倍增管，以产生具有有用的轴向场的断层摄影。 沿所有三个图像轴沿着采集至少12 cm和2 mm数据的视图。 使用单个NaI（T1）晶体不仅可以显著地 降低了系统复杂度和成本，而且具有良好的空间、定时和 能量分辨率 在项目的第一阶段， 圆柱形晶体和检测符合在一个单一的连续 晶体被证明。 在第二阶段，我们打算建造和测试一个 单晶体断层扫描仪的原型