MINORITY HIGH SCHOOL STUDENT RESEARCH APPRENTICE PROGRAM

这项提案要求为怀特黑德研究所提供资金 生物医学研究(WI)将购买灵敏、自动化的 蛋白质测序仪，研究人员可在以下地址获得 以及麻省理工学院癌症研究中心和 生物系。定序器将是美国海军陆战队的 蛋白质分析和合成实验室，已经提供服务 麻省理工学院生物界。Wi致力于其长期发展 运营和维护，并将提供资金聘请 由技术人员监督定序器的操作，并 为用户提供技术专业知识。一种蛋白质测序仪 将是许多小灵通资助的研究项目中必不可少的工具 在这里进行的，例如我们对结构和功能的研究 肠刷缘、组氨酸调节的研究 酵母菌的生物合成及其分子生物学研究 脊髓灰质炎病毒--酵母RNA的遗传和生化分析 聚合酶和我们对癌基因相互作用的研究 开发中的系统。

This proposal requests funds for the Whitehead institute for Biomedical Research (WI) to purchase a sensitive, automated protein sequenator which would be available to investigators at WI, as well as the M.I.T. Center for Cancer Research and the Department of Biology. The sequenator would be part of WI's Protein Analysis and Synthesis Laboratory, which already serves the WI-MIT biology community. WI is committed to its long term operation and maintenance and would provide funds to hire a technical person to supervise the operation of a sequenator and to provide technical expertise to the users. A protein sequenator would be essential tool in many PHS-supported research projects going on here, such as our studies on the structure and function of the intestine brush border, studies on the regulation of histidine biosynthesis in yeast, studies on the molecular biology of poliovirus, a genetic and biochemical analysis of yeast RNA polymerase, and our research on the interactions of oncogenes with developing systems.