MINORITY HIGH SCHOOL STUDENT RESEARCH APPRENTICE PROGRAM

该提案要求为怀特黑德研究所提供资金， 生物医学研究（WI）购买一个敏感的，自动化的 蛋白质测序仪，将提供给研究人员在 WI，以及M.I.T.癌症研究中心和 生物学系。 测序仪将是WI 蛋白质分析和合成实验室，已经为 WI-MIT生物学社区 WI致力于其长期 并将提供资金， 监督测序仪操作的技术人员， 为用户提供技术支持。 一种蛋白质测序仪 将是许多PHS支持的研究项目的重要工具 比如我们对细胞结构和功能的研究 肠刷状缘，组氨酸调控的研究 酵母生物合成的分子生物学研究 脊髓灰质炎病毒，酵母RNA的遗传和生化分析 聚合酶，以及我们对癌基因相互作用的研究 发展系统。

This proposal requests funds for the Whitehead institute for Biomedical Research (WI) to purchase a sensitive, automated protein sequenator which would be available to investigators at WI, as well as the M.I.T. Center for Cancer Research and the Department of Biology. The sequenator would be part of WI's Protein Analysis and Synthesis Laboratory, which already serves the WI-MIT biology community. WI is committed to its long term operation and maintenance and would provide funds to hire a technical person to supervise the operation of a sequenator and to provide technical expertise to the users. A protein sequenator would be essential tool in many PHS-supported research projects going on here, such as our studies on the structure and function of the intestine brush border, studies on the regulation of histidine biosynthesis in yeast, studies on the molecular biology of poliovirus, a genetic and biochemical analysis of yeast RNA polymerase, and our research on the interactions of oncogenes with developing systems.