FINESSE NanoBio (Fabrication and Imaging of Neon-Etched Structures and Surfaces for Engineering, Nanoscience and Biotechnology)

FINESSE NanoBio（用于工程、纳米科学和生物技术的氖蚀刻结构和表面的制造和成像）

• 批准号: EP/R025355/1
• 负责人: Ronan Daly
• 金额: $ 309.28万
• 依托单位: University of Cambridge
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2018
• 资助国家: 英国
• 起止时间: 2018 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=EP%2FR025355%2F1
• 关键词: FINESSE; NanoBio; Fabrication; Imaging; Neon

The FINESSE NanoBio team is proposing a new UK capability in imaging, cross-sectioning and patterning materials that are traditionally very difficult to examine at the nano and sub-nanometre scale without seriously effecting their structure or behaviour. It is important that the UK is placed at the forefront of this research, enabling start-ups, SMEs and large companies to drive innovation and growth with stronger underpinning scientific understanding. To address this, the team is requesting funding for a customised Zeiss NanoFab tool that consists of:1. An ultra-high precision imaging capability (sub 0.5 nm) of conductive and non-conductive samples2. An ultra-high precision patterning and TEM sample preparation capability (2 nm) of the same range of samples3. A cryogenic sample handling system to enable imaging of biological materials and biological or fluid interfaces with materials and structures.The tool achieves this revolutionary performance by focusing a stream of helium ions onto the surface and measuring the subsequently released secondary electrons. Ions can also be used to remove material in their path for patterning or cross-sectioning materials. This system has three ion options, gallium for bulk removal, neon for additional polishing and cutting and helium for very careful polishing. This difference in behaviour is due to the lower mass of the ions.Direct writing of metals in 10nm feature sizes is also feasible with this system, which will enable electrical contacts to be fabricated to advanced functional materials to test, for example, their conductivity or electrochemical behaviour when making sensors.The requested support will have far-reaching impact through the projects and industrial partners of almost 50 research groups actively supporting this proposal in Cambridge, across 10 different Departments and 4 different Schools. This sphere of scientific influence is amplified by the strong support from 5 universities, 2 catapult organisations and 3 industrial network organisations, who represent an estimated 1500 companies.This incredible response by academics and industrial researchers means the facility will also drive new engagement and collaborations between these partiers and will foster collaboration, through for example the planned symposium and engagement events.The commissioning, access, outreach and management will be delivered by a small committee of experienced researchers and microscopy suite managers, with review and guidance from a larger steering group of EPSRC, industrial and academic partners to ensure fair access, an environment that fosters collaborations and postgraduate education.

FINESSE NanoBio团队提出了一种新的英国成像，横截面和图案化材料的能力，这些材料传统上很难在纳米和亚纳米尺度上进行检查，而不会严重影响其结构或行为。重要的是，英国处于这项研究的前沿，使初创企业，中小企业和大公司能够以更强的基础科学理解来推动创新和增长。为了解决这个问题，该团队正在申请资金用于定制Zeiss NanoFab工具，该工具包括：1.导电和非导电样品的超高精度成像能力（低于0.5 nm）2。具有超高精度的图案化和TEM样品制备能力（2 nm），可制备相同范围的样品3。一种低温样品处理系统，用于对生物材料以及生物或流体与材料和结构的界面进行成像。该工具通过将氦离子流聚焦到表面并测量随后释放的二次电子来实现这一革命性性能。离子也可用于去除其路径中的材料，以图案化或横截面材料。该系统有三种离子选择，镓用于大块去除，氖用于额外的抛光和切割，氦用于非常仔细的抛光。这种行为上的差异是由于离子的质量较低。使用该系统直接写入10 nm特征尺寸的金属也是可行的，这将使电接触能够制造成先进的功能材料以进行测试，例如，它们的导电性或电化学行为时，使传感器。所要求的支持将有很大的-通过近50个研究小组的项目和工业合作伙伴积极支持剑桥的这一提议，跨越10个不同的部门和4个不同的学校。这一科学影响力领域得到了5所大学、2个弹射组织和3个工业网络组织的大力支持，这些组织代表了大约1500家公司。学者和工业研究人员的这种令人难以置信的反应意味着该设施还将推动这些机构之间的新接触和合作并将促进合作，通过例如计划的研讨会和参与活动。委托，访问，推广和管理将由经验丰富的研究人员和显微镜套件经理组成的小型委员会提供，由EPSRC的更大指导小组进行审查和指导，工业和学术合作伙伴，以确保公平的机会，促进合作和研究生教育的环境。