COOPERATIVE AMBLYOPIA CLASSIFICATION STUDY

合作性弱视分类研究

• 批准号: 3559615
• 负责人: Suzanne P McKee
• 金额: $ 24.1万
• 依托单位: SMITH-KETTLEWELL EYE RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 1988
• 资助国家: 美国
• 起止时间: 1988-09-01 至 1991-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3559615
• 关键词: adolescence (12-20); amblyopia; computer assisted diagnosis; cooperative study; disease /disorder classification; eye disorder diagnosis; human subject; middle childhood (6-11); psychophysics; young adult human (21-34)

This application is a participating center application for the first phase of the Cooperative Amblyopia Classification Study, a multi- center, planned, protocol based project to examine the existing clinical classification of amblyopia and compare it with a classification derived from the performance of the amblyopic eye on a set of specific psycho-physical tests. The data that emerge will be analyzed: - To determine a set of visual behaviors that distinguish amblyopic from normal eyes. - To determine clusters of visual behaviors that define different types of amblyopia. - To determine the correlation between types derived from psychophysical and oculomotor measures and clinical measures collected on the same patients. The statistical techniques of cluster analysis will be used on the measured clinical and psychophysical variables to examine the null hypothesis that the cluster of psychophysical measures can be predicted from the clinical classification and vice versa. The population studied will be amblyopic subjects, control subjects with clinical conditions usually associated with amblyopia but without the amblyopia and normal subjects. Ages range from 8 to 35 years. Full details of the project are contained in the Manual of procedure which accompanied the Lead Grant application.

此应用程序是第一个参与中心的应用程序 合作性弱视分类研究的阶段，一个多- 中心，计划，基于协议的项目，以检查现有的 弱视的临床分型，并与A 根据弱视眼的表现进行分类 进行一系列特定的心理和生理测试 出现的数据 将分析： - 为了确定一组视觉行为， 弱视与正常眼睛不同。 - 为了确定视觉行为的集群， 弱视的类型 - 派生的类型之间的相关性 心理物理和眼科测量以及临床测量 收集到的数据 聚类分析的统计技术将用于 测量临床和心理物理变量，以检查 零假设，心理物理测量的集群可以是 从临床分类预测，反之亦然。 的 研究人群为弱视受试者、对照受试者 临床症状通常与弱视有关， 不存在弱视和正常受试者。 年龄从8岁到 35年 该项目的全部细节载于《手册》 的程序，其中伴随着铅赠款申请。