Rapid catalytic disinfection of surfaces, PPE and transportation

卡迪夫大学和塞尔登研究中心有一种专利的新型催化方法，可以使长寿命的活性氧有效地杀死病原体和表面消毒。https://patentimages.storage.googleapis.com/12/c4/b7/8f1ef5827dc436/GB2572364A.pdfThe方法是使用喷雾瓶将含有稀释过氧化氢（H2O2）的环保溶液通过喷嘴内的催化剂（氧化铝基体上的铜盐）。我们对包括金黄色葡萄球菌和白色念珠菌酵母在内的一系列微生物进行了测试，并在几分钟内实现了99.999%的减少。到目前为止，我们还没有研究杀病毒活性，但鉴于我们的方法对其他微生物的影响，我们预计它对包膜病毒将是有效的。到目前为止，我们的工作主要集中在开发食品制备和农业工业的方法，关键是在处理的表面上没有有毒残留物，同时也提供了出色的杀灭效果和与处理表面的相容性。该研究计划将首先测试我们现有制剂对病毒的杀病毒活性，包括冠状病毒标准试验菌株作为SARS-CoV-2 （COVID-19）的替代品。然后，我们将致力于修改和简化配方，以确定我们是否可以用空气代替过氧化氢，同时保持病毒活性。我们还将开发气溶胶的使用，使新方法可用于处理大空间，可用于重复使用的个人防护用品消毒或交通工具（如救护车、公共汽车、火车和飞机的内部空间）的环境无毒消毒。

Cardiff University and Selden Research have a patented novel catalytic method of making long lived reactive oxygen species effective for pathogen kill and surface disinfection. https://patentimages.storage.googleapis.com/12/c4/b7/8f1ef5827dc436/GB2572364A.pdfThe method involves passing an environmentally benign solution containing dilute hydrogen peroxide (H2O2) using a spray bottle through a catalyst (a copper salt on alumina matrix) incorporated in the nozzle. We have tested this with a range of microorganisms includingStaphylococcus aureus and Candida albicans yeast and have achieved 99.999% reduction in minutes. To date we have not examined virucidal activity but given the effect of our method on other microorganisms we anticipate it will be effective against enveloped viruses. Our work untilnow focussed on developing the method for the food preparation and agricultural industries and the key point is that no toxic residues remain on the surfaces that are treated, while also offering exceptional kill efficacy and compatibility with the surfaces treated.The research programme will initially test the virucidal activity of our existing formulation on viruses including coronavirus standard test strain as a surrogate for SARS-CoV-2 (COVID-19). We will then aim to modify and simplify the formulation to determine if we can replace hydrogenperoxide by air whilst maintaining the virucidal activity. We will also develop the use of aerosols so that the new method can be used to treat large spaces which could be applied in the disinfection of PPE for reuse or the environmentally non-toxic disinfection of transportation such as the internal spaces of ambulances, buses, trains and planes.