Rapid air and surface disinfection using dry hydrogen peroxide

使用干燥过氧化氢快速空气和表面消毒

• 批准号: EP/W010836/1
• 负责人: Graham Hutchings
• 金额: $ 24.76万
• 依托单位: CARDIFF UNIVERSITY
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2021
• 资助国家: 英国
• 起止时间: 2021 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=EP%2FW010836%2F1
• 关键词: Rapid; air; surface; disinfection; using

We have formulated a catalyst capable of generating gas phase H2O2 (or dry hydrogen peroxide (DHP)) in significant concentrations (Akram et al. Chem. Sci., 2016, 7, 5833) using very dilute hydrogen concentrations of H2 in air at ambient temperature. Sub ppm levels of DHP are known to be highly effective in disinfecting airborne pathogens and two companies (Synexis and CASPR; https://synexis.com/; https://casprgroup.com/ ) have commercialised devices for disinfecting air with DHP procured and synthesised non-catalytically. We now propose an innovative catalytic approach. Our innovations in liquid phase H2O2 synthesis (Europe 17728642.4; 14753141.2; 16704892.5; US 9340423) has proven enhanced disinfection is achieved when H2O2 is synthesised using a catalyst. Simultaneous to H2O2 production, highly reactive short-lived oxygen species are also formed, and results in improved pathogen kill by over a million-fold compared to commercial H2O2 alone. We consider that a similar enhancement will result from a catalytic approach to DHP formation.We aim to utilise this discovery to design a novel catalysed route to DHP to disinfect air and surfaces in occupied spaces. We will use electricity to electrolyse water to produce low concentrations of hydrogen which is subsequently reacted with air over the gold-palladium catalyst producing gaseous DHP in such a way that all the hydrogen is totally consumed. The aim is to continually generate DHP at sub ppm levels (a maximum of 1ppm (1.4 mg H2O2 / cubic meter) of H2O2 averaged over a 8 hour period is allowed) and introduce this into flowing air that will disinfect both the air and surfaces. While the immediate focus is tackling the current Covid-19 pandemic the project aims to tackle the longer term and ongoing need for continuous air and surface disinfection for a range of pathogens

我们已经制定了一种能够在显著浓度下产生气相过氧化氢(或干式过氧化氢)的催化剂(Akram等人)。化学。科学，2016，7,5833)在环境温度下使用非常稀薄的氢在空气中的浓度。DHP的含量低于ppm，已知对空气中的病原体进行高效消毒，两家公司(Synexis和CASPR；https://synexis.com/；https://casprgroup.com/)已将以非催化方式获得和合成的DHP用于空气消毒的设备商业化。我们现在提出一种创新的催化方法。我们在液相过氧化氢合成方面的创新(欧洲17728642.4；14753141.2；16704892.5；美国9340423)已经证明，当使用催化剂合成过氧化氢时，可以实现增强消毒。在产生过氧化氢的同时，还会形成高活性的短寿命氧物种，与商业过氧化氢相比，病原体的杀灭效果提高了100万倍以上。我们认为，催化生成DHP的方法也将产生类似的增强效果。我们的目标是利用这一发现设计一种新的催化方法来生成DHP，以消毒占用空间中的空气和表面。我们将使用电力电解水来产生低浓度的氢，然后在金-钯催化剂上与空气反应生成气态DHP，这样所有的氢都被消耗殆尽。其目的是在低于ppm的水平上持续产生DHP(允许在8小时内平均产生1ppm(1.4 mg H_2O_2/立方米)的H_2O_2)，并将其引入流动的空气中，对空气和表面进行消毒。虽然当前的重点是应对当前的新冠肺炎大流行，但该项目旨在解决对一系列病原体进行持续空气和表面消毒的长期和持续需求