MOLECULAR BIOLOGY INFORMATION RESOURCE

该项目的重点是开发集成软件，以支持 分子生物学研究。 这项研究的基础是 在项目的前六年完成，并扩展了一个系统， 用于集成软件工具，叫做基因实验室。 基因实验室系统将 将现有的数据存储系统替换为 基于商业DBMS的面向对象解决方案。 全面 和国家的最先进的分析工具集将开发的援助， 与算法开发人员的几个关键合作。 一个先进的， 交互式应用程序，用于在 将开发核苷酸和蛋白质序列。 GeneLab系统 将与开发的补充分析系统集成， 哈佛，遗传数据环境，双方互利 项目 本项目期间开发的软件设计将 通过与软件的最终用户的密切互动来辅助。 的 作为这项研究的结果产生的软件将很快 传播给大量的研究人员谁是用户， 贝勒医学院的计算资源， 科罗拉多，MBCRR和哈佛大学。

The focus of this project is to develop integrated software to support molecular biology research. The research proposed builds on work completed during the first six years of the project and extends a system for integrating software tools called GeneLab. The GeneLab system will be improved by replacing its existing data storage system with an object-oriented solution based on a commercial DBMS. A comprehensive and state-of-the art analytical toolset will be developed with the aid of several key collaborations with algorithm developers. An advanced, interactive application for exploring and annotating information in nucleotide and protein sequences will be developed. The GeneLab system will be integrated with a complementary analytical system developed at Harvard, the Genetic Data Environment, to the mutual benefit of both projects. The design of software developed during this project will be aided by close interaction with the end users of the software. The software produced as a result of this research will be quickly disseminated to a large number of researchers who are users of computational resources at Baylor College of Medicine, University of Colorado, the MBCRR, and Harvard University.