MOLECULAR BIOLOGY INFORMATION RESOURCE

本项目的重点是开发集成软件，以支持 分子生物学研究。提出的研究是建立在工作的基础上的 在项目的头六年内完成，并扩展了一个系统 用于集成名为genLab的软件工具。GeneLAB系统将 通过将其现有数据存储系统替换为 基于商业数据库管理系统的面向对象解决方案。一个全面的 并将在援助下开发最先进的分析工具集 与算法开发人员的几个关键合作。一个先进的， 用于浏览和注释信息的交互式应用程序 将开发核苷酸和蛋白质序列。基因实验室系统 将与开发的补充分析系统集成在一起 哈佛，基因数据环境，对双方都有利 项目。在这个项目期间开发的软件的设计将是 借助与软件终端用户的密切交互。这个 作为这项研究的结果而产生的软件将很快 向大量研究人员传播，他们是 加州大学贝勒医学院的计算资源 科罗拉多州、MBCRR和哈佛大学。

The focus of this project is to develop integrated software to support molecular biology research. The research proposed builds on work completed during the first six years of the project and extends a system for integrating software tools called GeneLab. The GeneLab system will be improved by replacing its existing data storage system with an object-oriented solution based on a commercial DBMS. A comprehensive and state-of-the art analytical toolset will be developed with the aid of several key collaborations with algorithm developers. An advanced, interactive application for exploring and annotating information in nucleotide and protein sequences will be developed. The GeneLab system will be integrated with a complementary analytical system developed at Harvard, the Genetic Data Environment, to the mutual benefit of both projects. The design of software developed during this project will be aided by close interaction with the end users of the software. The software produced as a result of this research will be quickly disseminated to a large number of researchers who are users of computational resources at Baylor College of Medicine, University of Colorado, the MBCRR, and Harvard University.