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REGULATION OF EUKARYOTIC GENE EXPRESSION

REGULATION OF EUKARYOTIC GENE EXPRESSION
真核基因表达的调控
批准号:
3280005
负责人:
CHARLES B LAWRENCE
金额:
$9.86万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
1984
资助国家:
美国
项目状态:
已结题
起止时间:
1984-09-26 至 1987-08-31

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项目成果

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中文摘要
翻译
来自多方面调查的证据表明,该组织扮演着复杂的角色
英文摘要
Evidence from many lines of investigation suggest a complex role for the sequences at the 5 feet-terminus of eukaryotic mRNAs in determining the efficiency with which translation is initiated. We propose to systematically mutate in vitro the gene for a specific adenovirus type 5 mRNA, reincorporate the mutated gene into the viral genome and then measure the effect of the various mutations on the efficiency of translation of the mutated mRNA using an in vivo assay which has been developed in this lab. This approach will define the sequences at the 5 feet-terminus of mRNAs which are important in determining the efficiency of translation under physiological conditions.
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HICSS-26 CONFERENCE--MINITRACK ON GENOME INFORMATICS
  • 批准号:
    3435541
  • 项目类别:
  • 资助金额:
    $1.22万
  • 财政年份:
    1992
  • 负责人:
    CHARLES B LAWRENCE
  • 依托单位:
MOLECULAR BIOLOGY INFORMATION RESOURCE
  • 批准号:
    3450367
  • 项目类别:
  • 资助金额:
    $18.54万
  • 财政年份:
    1991
  • 负责人:
    CHARLES B LAWRENCE
  • 依托单位:
MOLECULAR BIOLOGY INFORMATION RESOURCE
  • 批准号:
    3450365
  • 项目类别:
  • 资助金额:
    $34.63万
  • 财政年份:
    1991
  • 负责人:
    CHARLES B LAWRENCE
  • 依托单位:
MOLECULAR BIOLOGY RESEARCH SUPPORT SYSTEM
  • 批准号:
    3519165
  • 项目类别:
  • 资助金额:
    $19.35万
  • 财政年份:
    1985
  • 负责人:
    CHARLES B LAWRENCE
  • 依托单位:
海外基金