LYMPHOCYTE BIOLOGY PROGRAMS

这个淋巴细胞中心补助金的目的是支持基础研究计划 在细胞免疫学和免疫遗传学的几个研究人员在 哈佛医学院病理学系。 我们认为通过整合 这些研究项目在行政上，同时仍然保留其 科学地认同，我们实现了几个重要的目标， 在以前的个人资助制度下得到了优化。 A.我们将 在更大程度上利用公共设备、设施和人员， 共享服务范畴下的经济方式。 B）我们可以建造更多 有效地，融资，并保持这样的独特资源：1）宝贵的 近交H-2同源和重组菌株，同种异型同源菌株， 在Dorf博士的监督下在我们的动物设施中饲养， 可供本项目所有研究人员使用， 外部调查人员; 2）由Mescher博士领导的生化实验室， 施普林格博士的两个特别有天赋的学生， 因子、巨噬细胞产物和H-2基因产物将被表征， 与相关调查人员合作。 C.可以增加 互动、协作和将我们的生产力放大了许多倍。 过去这种富有成果的合作或计划在 这个计划的成员之间的未来太多了，无法描述。 详细 这种合作研究目前正在博士之间进行。 Benacerraf的团队和Dorf博士，Unanue博士，Mescher博士，Unanue博士 Dorf博士，Mescher博士和Ault博士，仅举几个正在进行的 项目

This Lymphocyte Center Grant is designed to support the basic research programs in cellular immunology and immunogenetics of several investigators in the Department of Pathology at Harvard Medical School. We feel that by integrating these research projects administratively, while still preserving their identities scientifically, we achieved several important aims which were not optimized under the previous system of individual funding. Thus, a) We will achieve a greater usage of common equipment facilities and personnel in a more economical way under the category of shared services. b) We can build more effectively, finance, and maintain such unique resources as: 1) the precious inbred H-2 congenic and recombinant strains, allotype congenic strains which are maintained in our animal facility under the supervision of Dr. Dorf and which are available for the work of all the investigators in this project as well as outside investigators; 2) a biochemical laboratory headed by Drs. Mescher and Springer, two exceptionally gifted students of Dr. Strominger, where the T cell factors, macrophage products and H-2 gene products will be characterized in collaboration with the respective concerned investigators. c) We can increase the interactions, collaborations and magnify our productivity many folds. Examples of such fruitful collaboration in the past or planned cooperation in the future between members of this program are too numerous to describe in detail. Such collaborative studies are presently pursued between Dr. Benacerraf's group and Dr. Dorf, Dr. Unanue, Dr. Mescher, between Dr. Unanue and Dr. Dorf, Dr. Mescher and Dr. Ault to mention only a few of the ongoing projects.