DESIGN OF PEDIATRIC COCHLEAR IMPLANTS

本项目的重点是设计方面的多合同人工耳蜗 植入物集中在影响他们的能力的因素， 移除并替换，可能使用尺寸不同的植入物。 的 新的设计必须引起最小的机械创伤和异物反应 在中耳和内耳结构中。 预计这将 包括表面材料、电极几何形状 与现有电极相比，植入物固定技术 阵 评价将在非聋动物模型的发展 孩子 使用非聋人模型的决定是基于这样一个事实， 毛细胞是耳蜗结构紊乱的敏感指标 和功能 此外，在植入电极阵列的失聪模型中， 诱发耳聋造成的耳蜗损伤， 解释植入物本身造成的损伤。

This project focuses on the design aspects of multicontract cochlear implants concentrating on the factors that affect their ability to be removed and replaced, possibly with dimensionally different implants. The new designs must cause minimal mechanical trauma and foreign body reaction in middle and inner ear structures. It is anticipated that this will include improvements in surface materials, electrode geometries and implant fixation techniques as compared with presently existing electrode arrays. Evaluation will be in non-deaf animal models of the developing child. The decision to use a non-deaf model is based on the fact that hair cells are sensitive indicators of disturbances of cochlear structure and function. Also, in deaf models with implanted electrode arrays, cochlear damage produced by inducing deafness complicates the interpretation of damage caused by the implant itself.