课题基金 / 基金详情

STRUCTURAL STUDIES OF AIDS PROTEINS BY NMR

STRUCTURAL STUDIES OF AIDS PROTEINS BY NMR
通过核磁共振对艾滋病蛋白进行结构研究
批准号：
3754175
负责人：
A M GRONENBORN
金额：
$0.0万
依托单位：
NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/3754175
关键词：
DNA binding protein RNA binding protein cytokine genetic enhancer element genetic regulatory element human immunodeficiency virus 1 interleukin 1 interleukin 4 interleukin 8 nuclear magnetic resonance spectroscopy nucleocapsid protein folding protein structure transcription factor virus protein

项目摘要

项目成果

A M GRONENBORN的其他基金

相似基金

相关文献

中文摘要
翻译
已经就与以下方面有关的一些结构问题开展了工作 源自HIV病毒的蛋白质。其中包括p7核衣壳。 HIV-1的蛋白质和nef，以及免疫系统的蛋白质，在 特异性人巨噬细胞炎性蛋白-1-β、白介素8 和白介素4。P7核衣壳的RNA结合特性 已经对蛋白质进行了研究，并对一种特定的p7- RNA复合体已经启动。此外，在建筑群上的工作 转录因子GATA-1及其同源DNA靶点已被 追踪以识别和定位束缚水。
英文摘要
Work has been carried out on a number of structural problems related to proteins derived from the HIV virus. These include the p7 nucleocapsid protein and nef of HIV-1, and proteins of the immune system, in particular human macrophage inflammatory protein-1-beta, interleukin-8 and interleukin-4. The RNA binding properties of the p7 nucleocapsid protein have been investigated and structural studies of a specific p7- RNA complex have been initiated. In addition, work on the complex of the transcription factor GATA-1 with its cognate DNA target site has been pursued to identify and localize bound water.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
INVESTIGATIONS OF MACROMOLECULAR STRUCTURES AND DYNAMICS IN SOLUTION BY NMR
STRUCTURAL STUDIES OF AIDS PROTEINS BY NMR
INVESTIGATIONS OF MACROMOLECULAR STRUCTURES IN SOLUTION BY NMR
INVESTIGATIONS OF MACROMOLECULAR STRUCTURES AND DYNAMICS IN SOLUTION BY NMR
海外基金