INSULIN SENSITIVITY & GLUCOSE HOMEOSTASIS IN NIDDM ADDOLESCENTS

胰岛素敏感性

• 批准号: 3761438
• 负责人: KWAME OSEI
• 金额: --
• 依托单位: OHIO STATE UNIVERSITY
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3761438
• 关键词: African American; adolescence (12-20); body composition; caucasian American; diabetes mellitus genetics; epidemiology; family genetics; glucose metabolism; homeostasis; human subject; insulin sensitivity /resistance; noninsulin dependent diabetes mellitus; racial /ethnic difference

Epidemiological studies have demonstrated that black Americans have a 2-3 fold higher prevalence of type 2 diabetes as well as an earlier age of onset. This study evaluates the insulin sensitivity indices as well as the impact of family history and race on glucose homeostasis of type 2 diabetes black and white adolescent populations. Relationships between body composition variables and insulin sensitivity indices in the adolescent population in both races will be examined.

流行病学研究表明，美国黑人有2-3