CORRELATES OF GROWTH HORMONE DEFICIENCY

生长激素缺乏的相关因素

• 批准号: 3763693
• 负责人: RAPHAEL R DAVID
• 金额: --
• 依托单位: NEW YORK UNIVERSITY
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3763693
• 关键词: biomarker; child (0-11); endocrine disorder diagnosis; excretion; human subject; insulinlike growth factor; pharmacokinetics; pituitary dwarfism; urinalysis

The purpose of this study is to measure IGF-1, and IGF1-BP3 in children with short stature, and correlate the results with other indices, including plasma GH levels (post stimulation), and urinary GH excretion. The aim is to determine which of these parameters provide the best discriminant in the diagnosis of Growth Hormone Deficiency.

本研究的目的是检测儿童IGF-1和IGF 1-BP 3的水平， 并将结果与其他指标相关联， 包括血浆GH水平（刺激后）和尿GH排泄。 目的是确定这些参数中哪一个提供最佳的 生长激素缺乏症的诊断。