PROGNOSTIC INDICATORS OF GONADOTROPIN DEFICIENCY

促性腺激素缺乏的预后指标

• 批准号: 3863955
• 负责人: RAPHAEL R DAVID
• 金额: --
• 依托单位: NEW YORK UNIVERSITY
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3863955
• 关键词: adrenal glands; clinical trials; follicle stimulating hormone; gonadotropin releasing factor; gonadotropins; hormone regulation /control mechanism; human puberty; human subject; hypogonadism; luteinizing hormone; progesterone analog; prognosis; prolactin; prolactin releasing /inhibiting factor; thyrotropin releasing hormone

In order to differentiate constitutional delayed puberty from hypothalamic hypogonadism, this study examines the utility of conjoint use of multiple parameters, including LHRH testing of LH, FSH, prolactin responsiveness to TRH and a sleep-entrained episodic secretion of LH and FSH along with serial measurements of 17 hydroxy-progesterone and other indices of adrenarche.

为了鉴别体质性青春期延迟与下丘脑性青春期延迟， 性腺功能减退症，这项研究探讨了联合使用多种 参数，包括LH，FSH，催乳素反应性的LHRH测试， TRH和睡眠引起的LH和FSH的间歇性分泌， 连续测量17羟孕酮和其他指标， 肾上腺功能亢进