PLACEBO CONTROLLED COMPARATIVE TRIAL OF CHOLESTYRAMINE TABLETS

考来烯胺片的安慰剂对照比较试验

• 批准号: 3767251
• 负责人: JOHN ROBIN CROUSE
• 金额: --
• 依托单位: WAKE FOREST UNIVERSITY
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3767251
• 关键词: blood disorder chemotherapy; cholesterol; cholestyramine; clinical trials; combination chemotherapy; drug screening /evaluation; human subject; human therapy evaluation; hypercholesterolemia; low density lipoprotein; oxidoreductase inhibitor

The bile acid binding resin, cholestyramine, has been shown to be an important cholesterol-lowering agent. This trial will test its efficacy for lowering LDL cholesterol alone and in combination with a reductase inhibitor, pravastatin. This study is a randomized, double-blind, placebo-controlled multicenter trial in hypercholesterolemic patients.

胆汁酸结合树脂考来烯胺已被证明是一种 重要降胆固醇剂。 这次试验将测试它的功效 用于单独和与还原酶组合降低LDL胆固醇 抑制剂，普伐他汀。 本研究是一项随机、双盲、 高胆固醇血症患者的安慰剂对照多中心试验。