IMAGING OF BIOLOGICAL TISSUES USING HIGH-FREQUENCY INTENSITY-MODULATED LIGHT

使用高频强度调制光对生物组织成像

• 批准号: 3789428
• 负责人: J M SCHMITT
• 金额: --
• 依托单位: NATIONAL CENTER FOR RESEARCH RESOURCES
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3789428
• 关键词: biomedical equipment development; clinical biomedical equipment; image enhancement; imaging /visualization /scanning; infrared spectrometry; method development

Our efforts this year were concentrated on identifying the practical limitations of diffusing-wave interference spectrophotometry in the context of thick-tissue imaging for clinical application. This goal was achieved by using a combination of theoretical and experimental investigations. We found that although it is possible to determine very precisely the position of a single object embedded deep in a homogeneous medium, the resolution of two or more absorbing (or fluorescent) objects is limited by the width of the diffusive-wave point-spread function, which exceeds about 5 mm at the highest modulation frequencies studied.

我们今年的工作集中在确定实际情况上